Most cited article - PubMed ID 12822088
A prospective, randomized trial comparing endoscopic and surgical therapy for chronic pancreatitis
Pain is a common symptom of many diseases. Recently, the pain has been classified and analyzed exactly. Its particular components/types are described to the maximum of their depths and details. That is why each particular pain present in a specific disease (pancreatopathies included) has to be treated according to the presence of the specific type of pain. In diseases of pancreas, there are nociceptive, neuropathic, and inflammatory components of pain participating, frequently. Especially long-lasting, not well-controlled pain sets off the process of neuromodulation. The recent pioneering applications/administrations of various neuromodulatory therapeutic approaches represent the promising discoveries for the treatment of long-term, severe, drug-resistant pain syndromes, including chronic pancreatitis. In this article, we summarized the characteristics of pain, the therapeutic strategy, and algorithms of analgesic treatment (in general and applied for pancreatopathies), including new therapeutic trends and approaches.
- MeSH
- Chronic Pain physiopathology therapy MeSH
- Pancreatitis, Chronic physiopathology therapy MeSH
- Humans MeSH
- Pain Management methods MeSH
- Inflammation Mediators metabolism MeSH
- Pancreatic Diseases physiopathology therapy MeSH
- Neuralgia physiopathology therapy MeSH
- Neuronal Plasticity physiology MeSH
- Neurotransmitter Agents physiology MeSH
- Nociceptors physiology MeSH
- Pancreas innervation MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Inflammation Mediators MeSH
- Neurotransmitter Agents MeSH