BACKGROUND: Panniculitis-like T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma, occurring usually in the form of nodules within the subcutaneous fat tissue of the extremities or trunk. In the literature, subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is described as a distinct type of T-cell lymphoma with a variable clinical behavior, depending on molecular phenotype of T-cell receptor (TCR) and on the presence or absence of hemophagocytic syndrome. CASE PRESENTATION: We present a bioptic and autoptic case of a 65-years old Caucasian man with panniculitic T-cell lymphoma with morphological and immunohistochemical features of SPTCL, limited to the retroperitoneal and mesenteric mass, i.e. without any cutaneous involvement, and associated with severe hemophagocytic lymphohistiocytosis. CONCLUSION: A panniculitic T-cell lymphoma with morphological and molecular features of SPTCL, which is limited to mesentery, i.e. does not involve subcutaneous fat, seems to be exceedingly rare.

• Keywords
• Hemophagocytosis, Lymphohistiocytosis, Mesentery, Panniculitis, T-cell lymphoma,
• MeSH
• Diagnosis, Differential MeSH
• Lymphoma, T-Cell, Cutaneous diagnosis   pathology   MeSH
• Humans MeSH
• Lymphohistiocytosis, Hemophagocytic diagnosis   pathology   MeSH
• Lymphoma, T-Cell diagnosis   pathology   MeSH
• Skin Neoplasms diagnosis   pathology   MeSH
• Panniculitis diagnosis   pathology   MeSH
• Autopsy MeSH
• Aged MeSH
• T-Lymphocytes pathology   MeSH
• Check Tag
• Humans MeSH
• Male MeSH
• Aged MeSH
• Publication type
• Journal Article MeSH
• Case Reports MeSH