The ability of bacteriophages to survive under unfavorable conditions is highly diversified. We summarize the influence of different external physical and chemical factors, such as temperature, acidity, and ions, on phage persistence. The relationships between a phage's morphology and its survival abilities suggested by some authors are also discussed. A better understanding of the complex problem of phage sensitivity to external factors may be useful not only for those interested in pharmaceutical and agricultural applications of bacteriophages, but also for others working with phages.

• MeSH
• bakteriofágy klasifikace   účinky léků   fyziologie   MeSH
• ionty farmakologie   MeSH
• koncentrace vodíkových iontů MeSH
• osmotický tlak MeSH
• teplota MeSH
• životní prostředí MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH
• Názvy látek
• ionty MeSH

The treatment of three patients suffering from chronic bacterial prostatitis who were qualified for an experimental phage therapy protocol managed at the Phage Therapy Unit in Wrocław is described. They had previously been treated unsuccessfully with long-term targeted antibiotics, autovaccines, and laser biostimulation. Rectal application of phage lysates targeted against Enterococcus faecalis cultured from the prostatic fluid gave encouraging results regarding bacterial eradication, abatement of clinical symptoms of prostatitis, and lack of early disease recurrence.

• MeSH
• bakteriofágy chemie   fyziologie   MeSH
• biologická terapie * MeSH
• dospělí MeSH
• Enterococcus faecalis izolace a purifikace   virologie   MeSH
• grampozitivní bakteriální infekce mikrobiologie   terapie   MeSH
• lidé MeSH
• prostatitida mikrobiologie   terapie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH