Recently deceased professor Luboslav Stárka was a world-renowned doctor who devoted his whole life to the study and therapeutic use of steroids, and was particularly interested in vitamin D. He knew from his own experience and from deep knowledge that this vitamin, one of the oldest steroids in development, must have a number of effects in addition to the undeniably positive effects on bones. He commissioned our task force to address the issues surrounding vitamin D, leading to years of studies with robust results made possible by the use of chromatography coupled with mass spectrometry (LC-MS), a so-called gold standard of measurement that is a cornerstone of recent scientific studies. This led to a whole series of scientific publications, the aim of which was to point out the possibility of using the abilities of vitamin D and thus also the gift that nature has given us.

• MeSH
• chromatografie kapalinová MeSH
• hormony MeSH
• lidé MeSH
• steroidy * MeSH
• vitamin D * MeSH
• vitaminy MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• hormony MeSH
• steroidy * MeSH
• vitamin D * MeSH
• vitaminy MeSH

Vitamin D is no longer considered an agent only affecting calcium phosphate metabolism. A number of studies over the past few years have demonstrated its role in immunomodulation and its influence on the development and functioning of the brain and nervous system. In the current epidemiological crisis caused by coronavirus disease 2019 (COVID-19), the immunoprotective role of vitamin D has been discussed by some authors regarding whether it contributes to protection against this serious disease or whether its use does not play a role. Non-standard approaches taken by laboratories in examining the serum levels of the vitamin D metabolite calcidiol have contributed to inconsistent results. We examined the serum of 60 volunteers in the spring and autumn of 2021 who declared whether they were taking vitamin D at the time of sampling. Furthermore, the tested participants noted whether they had experienced COVID-19. A newly developed liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was used to measure calcidiol levels. The analysis of variance (ANOVA) model of Statgraphics Centurion 18 statistical software from Statgraphics Technologies was used for calculations. The results of this study showed that those who took vitamin D suffered significantly less often from COVID-19 than those who did not take vitamin D.

• Klíčová slova
• COVID-19, LC-MS/MS determination, vitamin D,
• MeSH
• chromatografie kapalinová metody   MeSH
• COVID-19 * epidemiologie   prevence a kontrola   MeSH
• kalcifediol MeSH
• lidé MeSH
• tandemová hmotnostní spektrometrie metody   MeSH
• vitamin D * metabolismus   MeSH
• vitaminy MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• kalcifediol MeSH
• vitamin D * MeSH
• vitaminy MeSH