Regenerative endodontic procedure (REP) is a progressive treatment modality for immature permanent teeth with necrotic pulp. The ambiguousness about the predictability of REP outcome in relation to complete disinfection of the root canal system and the occurrence of discoloration still exists. The aim of this retrospective study was to analyze two treatment protocols on clinical success rate, radiographic root development and the occurrence of discoloration. Eighteen patients were treated by a single operator by either treatment protocol according to the American Association of Endodontists (AAEP, n = 9) or a modified protocol (MP, n = 9) with the use of 5% sodium hypochlorite and sandblasting. Patients were followed up after 3, 6, 9, 12, 18 and 24 months and clinical success, radiographic root development and the occurrence of discoloration were assessed. The clinical success of MP was significantly higher in two years follow-up (p = 0.015), but the change in radiographic root area was higher for AAEP (p = 0.017) and the occurrence of discoloration was higher in AAEP (p = 0.029). The use of 5% sodium hypochlorite for a longer period of time leads to a higher success rate. The sandblasting of the access cavity reduces the occurrence of discoloration.

• Klíčová slova
• immature tooth, radiographic root area, regenerative endodontic procedure, root development,
• Publikační typ
• časopisecké články MeSH

Discoloration remains an unfavourable complication of otherwise successful regenerative endodontic procedure of immature teeth with necrotic pulp. This review presents a critical view on current knowledge of discoloration sources, its treatment and possible preventive modalities, dealing mainly with the use of antibiotics, ethylendiaminotetraacetic acid, calcium hydroxide, mineral trioxide aggregate, calcium silicate cements, sodium hypochlorite and chlorhexidin during regenerative treatment and their possible interactions. Bleaching as a discoloration treatment modality is discussed as well.

• Klíčová slova
• Biodentin, CEM cement, Calcium Hydroxide, Calcium Silicate, Mineral Trioxide Aggregate, Regenerative Medicine, Sodium Hypochlorite, Tooth Discoloration,
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

The aim of this article is to describe the clinical case of the non-surgical retreatment of a failed revascularization/revitalization treatment (RRT). The retreatment was preceded by two sessions including an interim medication with calcium hydroxide and a modified irrigation protocol containing a highly-concentrated sodium hypochlorite and prolonged usage of ethylenediaminetetraacetic acid (EDTA) to reverse unacceptable side effects of hypochlorite. During a 15- month follow-up, the healing of the periapical lesion, increased thickening of root canal walls and maturation of root was apparent. The repeated RRT represents a possible treatment modality for s failed RRT. Key words:Retreatment, revascularization, revitalization, maturogenesis, immature tooth.

• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH