Tumor-associated macrophages are an important part of the tumor microenvironment. The presence of certain populations of macrophages within tumor tissue may be associated with either better or worse disease prognosis. The study of these cells is currently receiving a great deal of attention, with the most important topics of investigation raised being: the typification of subpopulations of tumor-associated macrophages; identification of the prognostic significance of population density and distribution of macrophages in the tumor microenvironment; ways to influence macrophage activity, migration and differentiation within the tumor. The answers to these questions can improve the efficiency of immunoterapy for malignancies. The presented article briefly reviews recent findings on tumor-associated macrophages in solid malignancies.

• Keywords
• alternatively activated macrophages (M2), classically activated macrophages (M1), resident tissue macrophages (NTAMs), tumor microenvironment (TME), tumor-associated macrophages (TAMs),
• MeSH
• Humans MeSH
• Tumor-Associated Macrophages * MeSH
• Macrophages pathology   MeSH
• Tumor Microenvironment MeSH
• Neoplasms * MeSH
• Prognosis MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH
• Review MeSH