Chronic kidney disease (CKD) leads to profound metabolic and hemodynamic changes, which damage other organs, such as heart and brain. The brain abnormalities and cognitive deficit progress with the severity of the CKD and are mostly expressed among hemodialysis patients. They have great socio-economic impact. In this review, we present the current knowledge of involved mechanisms.

• MeSH
• Renal Insufficiency, Chronic complications   pathology   MeSH
• Cognition Disorders etiology   pathology   MeSH
• Humans MeSH
• Brain diagnostic imaging   pathology   MeSH
• Risk Factors MeSH
• Animals MeSH
• Check Tag
• Humans MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Review MeSH