Speech and language technologies are effective tools for identifying the distinct speech changes associated with Parkinson's disease (PD), enabling earlier and more accurate diagnosis. Models leveraging recent advancements in self-supervised speech pretraining, such as Wav2Vec, have demonstrated superior performance over traditional feature extraction methods. While Wav2Vec 2.0 has been successfully utilized for PD detection, a rigorous quantitative comparison with Wav2Vec 1.0 is needed to comprehensively evaluate its advantages, limitations, and applicability across different speech modes in PD. This study presents a systematic comparison of Wav2Vec 1.0 and Wav2Vec 2.0 embeddings across three multilingual datasets using various classification approaches to classify normal (healthy controls; HC) and PD-affected speech. Additionally, both Wav2Vec 1.0 and 2.0 were benchmarked against traditional baseline features across diverse linguistic contexts, including spontaneous speech, non-spontaneous speech, and isolated vowels. A multicriteria TOPSIS approach was employed to rank feature extraction methods, revealing that Wav2Vec 2.0 excelled across speech modes, with its first transformer layer demonstrating the best performance for classifying read text and monologue, and its feature extractor performing best in vowel-based classification. In contrast, Wav2Vec 1.0, while generally outperformed by Wav2Vec 2.0, still provided a more efficient alternative with competitive performance. Finally, we combined selected layers from both architectures and have demonstrated improved diagnostic accuracy in vowel-based classification. This comparative analysis underscores the strengths of both Wav2Vec architectures and informs their optimal use in PD detection.

• Keywords
• Classification, Parkinson's disease, Speech modes, Wav2vec 1.0, Wav2vec 2.0,
• Publication type
• Journal Article MeSH