Therapeutic strategy and clinical course of 28 low grade gliomas of the anterior visual tract were analyzed and compared with results of quantitative microscopic examination. Children operated on between 1978 and 1987 were divided into four groups according to the tumor site. DNA microfluorometry and image analysis of bioptic material were used for an objective differentiation between morphologically almost identical gliomas classified as pilocytic astrocytomas (grade I). Six cases of posttraumatic gliosis were examined as controls. Results were tested with factor analysis and by multiple comparison procedures. Significant differences between quantitative parameters of tumors located along the visual pathway were found with the use of computer-aided microscopy. These results corresponded with the clinical experience and patient's outcome. A radical surgical intervention (without additional oncologic therapy) was recommended for patients with intraorbital gliomas which revealed favorable quantitative microscopic features.

• MeSH
• astrocytom diagnóza   patofyziologie   chirurgie   MeSH
• biopsie MeSH
• dítě MeSH
• kojenec MeSH
• lidé MeSH
• nádory kraniálních nervů diagnóza   patofyziologie   chirurgie   MeSH
• nádory mozku sekundární   MeSH
• nemoci zrakového nervu diagnóza   patofyziologie   chirurgie   MeSH
• předškolní dítě MeSH
• Check Tag
• dítě MeSH
• kojenec MeSH
• lidé MeSH
• předškolní dítě MeSH
• Publikační typ
• časopisecké články MeSH