Nejvíce citovaný článek - PubMed ID 6053294
Difference in the proteolytic activity of spleen cells of young and immunologically mature rabbits
The activities of lysozyme, myeloperoxidase, and elastase were lower in PMNs and AMs from GF and AF Minnesota miniature piglets than in the leukocytes from their CONV counterparts. In the spleen and serum of gnotobiotic piglets only the levels of lysozyme were slightly reduced. Substantially depressed activities of these LEs were found also in PMNs from precolostral piglets in comparison with PMNs from their CONV mother. The bisassociation of GF piglets with Enterococcus liquefaciens and Escherichia coli caused an increase of LE activities in their AMs, spleens, and sera. Fewer LEs were released after phygocytic stimulation with zymosan from PMNs of GF, AF, and precolostral piglets than from PMNs of CONV animals of the same age. These data suggest that the antigenic-microbial stimulation is important for the development of normal lysosomal enzyme activities in PMNs and AMs from gnotobiotic animals.
- MeSH
- antigeny imunologie MeSH
- gnotobiologické modely * MeSH
- lyzozomy enzymologie MeSH
- makrofágy enzymologie MeSH
- miniaturní prasata MeSH
- neutrofily enzymologie MeSH
- prasata MeSH
- slezina enzymologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny MeSH
- MeSH
- antigeny aplikace a dávkování MeSH
- apendix imunologie MeSH
- časové faktory MeSH
- erytrocyty imunologie MeSH
- Escherichia coli imunologie MeSH
- hemaglutinační testy MeSH
- imunizace MeSH
- injekce intravenózní MeSH
- králíci MeSH
- lymfatický systém imunologie MeSH
- mezenterium imunologie MeSH
- ovce MeSH
- reakce antigenu s protilátkou MeSH
- Salmonella paratyphi A imunologie MeSH
- slezina imunologie MeSH
- střeva imunologie MeSH
- thymus imunologie MeSH
- tvorba protilátek * MeSH
- věkové faktory MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny MeSH