Addition of L-tryptophan to cultures of the basidiomycete Oudemansiella mucida brought about a pronounced increase of production of the antibiotic mucidin. The highest increase was reached in the presence of 0.15-0.20% tryptophan and after its addition to a l-d culture. The methyl ester of tryptophan exhibited the same effect. Mycelium growing during the initial phases in the presence of tryptophan synthesized mucidin powerfully during later phases of the fermentation.

• MeSH
• Alkenes biosynthesis   MeSH
• Antifungal Agents biosynthesis   MeSH
• Basidiomycota drug effects   metabolism   MeSH
• Methacrylates MeSH
• Fatty Acids, Unsaturated MeSH
• Strobilurins MeSH
• Tryptophan pharmacology   MeSH
• Publication type
• Journal Article MeSH
• Names of Substances
• Alkenes MeSH
• Antifungal Agents MeSH
• Methacrylates MeSH
• mucidin MeSH Browser
• Fatty Acids, Unsaturated MeSH
• Strobilurins MeSH
• Tryptophan MeSH