Traumatic bone lesions form an important part of the study of human paleopathology. Injuries of the skull are frequent in the history of the human race. 647 adult dry skulls of both sexes from the "Broumov Ossuary" (13th-18th century) were examined for the incidence of cranium injuries. In this paper, an extensive collection (n=122) of healed dry skull injuries is presented. In the neuro- and splanchnocranium of skulls (n=78), linear and depressed fractures, slash and stab wounds have been seen but no gunshot wound. In part of the skulls (n=29), multiple injuries have been observed. Many detected traumatic lesions seem to have been caused by traditional weapons of the last centuries: war swords, axes, or pole-arms with metal spikes. All the skull injuries show clear signs of well-healing with bone remodelling that indicates the survival of victims for a long period after the cranial trauma.

• MeSH
• dějiny 15. století MeSH
• dějiny 16. století MeSH
• dějiny 17. století MeSH
• dějiny 18. století MeSH
• dějiny středověku MeSH
• dospělí MeSH
• fraktury lebky dějiny   patologie   MeSH
• lidé MeSH
• paleopatologie MeSH
• vedení války * MeSH
• Check Tag
• dějiny 15. století MeSH
• dějiny 16. století MeSH
• dějiny 17. století MeSH
• dějiny 18. století MeSH
• dějiny středověku MeSH
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH
• historické články MeSH
• Geografické názvy
• Česká republika MeSH

Methods of processing and cryopreservation are believed to be the most important factors of long term clinical performance of biological heart valve prostheses. That is why we decided to cooperate in evaluating the impact of current AHV (allograft heartvalve) bank protocol on valve tissue morphology. AHV harvested from "heart-beating" cadaveric donors, considered as a fresh tissue, were compared with valve samples from non-heart beating donors, samples stored in saline, samples treated with antibiotic solution, and finally with cryopreserved valves, stored in liquid nitrogen for months. All samples were dissected, dried with hexamethyldisilazane (HMDS) method, gold-coated, studied and photographed in scanning electron microscope Tesla BS 301. Different superficial patterns were found on ventricular and vascular surfaces of "fresh" semilunar valves. We were able to detect early changes of endothelium after harvesting, denudation of endothelial covering during preservation with and without freezing. Our alternative method of drying samples by HMDS method proved to be suitable for thin membranes of human semilunar valves. Scanning electron microscopy seems to be helpful for morphological control of processing, cryopreservation and liquid nitrogen storage of AHV. We believe that further confrontation of morphological investigation with other methods helps us to develop more suitable protocol of handling AHV in heart valve banking.

• MeSH
• antibakteriální látky farmakologie   MeSH
• aortální chlopeň ultrastruktura   MeSH
• chlorid sodný MeSH
• kryoprezervace MeSH
• lidé MeSH
• mikroskopie elektronová rastrovací MeSH
• plicní chlopeň ultrastruktura   MeSH
• srdeční chlopně ultrastruktura   MeSH
• uchovávání tkání * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• antibakteriální látky MeSH
• chlorid sodný MeSH