In a sample of 3,757 men aged 40-50 years, all employees of a large industrial plant, the authors studied the prevalence of several risk factors (RF) of ischaemic heart disease (IHD) in relationship to profession and education of probands. Blue collar workers were more frequently heavy smokers and regular alcohol consumers than white collars. Compared with other workmen professions a tendency towards a higher risk profile was present in employees doing strenuous manual work. These were heavier smokers, had higher blood pressure and serum cholesterol. Within white-collar professions a higher risk profile was observed in managers with high responsibility than in personnel of the research and development departments. The former were heavier smokers, had higher serum cholesterol and greater overweight. The education level was in indirect association with smoking, hypertension and obesity but correlated directly with regular alcohol consumption. Socio-economic factors evidently influence the prevalence of risk factors of IHD also in the Czech industrial population.

• MeSH
• cholesterol krev   MeSH
• dospělí MeSH
• koronární nemoc etiologie   MeSH
• kouření MeSH
• lidé středního věku MeSH
• lidé MeSH
• obezita patofyziologie   MeSH
• pití alkoholu MeSH
• průmysl MeSH
• průřezové studie MeSH
• riziko MeSH
• socioekonomické faktory * MeSH
• výchova a vzdělávání MeSH
• zaměstnání MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH
• Názvy látek
• cholesterol MeSH

The glass clover snail, Monacha cartusiana (M. cartusiana) is one of the most seriously impacting economic animal pests spreading across Egypt which inflicts severe damages to the agriculture. A green route is developed by deploying an abundant Rosemary plant leaves aqueous extract to synthesize ZnO and F-doped ZnO (F-ZnO) nanoparticles (NPs) that display high molluscicidal activities against the M. cartusiana land snails via leaf dipping and contact techniques. The effect of lethal concentrations, that kills 50% of exposed snails (LC50) value of the treatments, is examined on the activity of alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), enzymes, total protein (TP), total lipids (TL) and cholesterol level of snails, including the histopathological evaluation of the digestive gland and foot of M. Cartusiana. Their molluscicidal activity as poisonous baits under field conditions is also evaluated and compared to the recommended molluscicide, Neomyl. The results show that F- doping dramatically improves the snail control capability of ZnO NPs, and promotes a considerable increase in both ALT and AST enzymes with an enhancement of TL and Cholesterol levels, but a significant decrease in TP content and ALP activity in treated snails compared to the control group. The LC50 values are found to be 1381.55 and 2197.59 ppm using the leaf dipping for F-ZnO and ZnO, while 237.51 and 245.90 ppm can be achieved using the contact technique, respectively. The greenly synthesized F-ZnO and ZnO NPs induce severe histological alterations in the digestive gland and foot of M. cartusiana, including a complete destruction of the digestive tubules. The histological evaluation of the foot of M. cartusiana exposed to ZnO, shows a rupture of the epithelial layer of the foot sole, while F- ZnO NPs causes the folds of the foot becoming deeper and the rupture of epithelial layer. Our field experiments further demonstrate that F-ZnO achieves 60.08% reduction, while ZnO attains 56.39% diminution in snail population compared to the commercial, Neomyl (69.55%), exhibiting great potentials in controlling the harmful land snail populations.

• Klíčová slova
• Green synthesis, Histopathological evaluation, Land snail, Molluscicidal activity, Monacha cartusiana, ZnO nanoparticles,
• MeSH
• cholesterol MeSH
• LD50 MeSH
• listy rostlin MeSH
• moluskacidy * toxicita   MeSH
• oxid zinečnatý * toxicita   MeSH
• rostlinné extrakty chemie   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• cholesterol MeSH
• moluskacidy * MeSH
• oxid zinečnatý * MeSH
• rostlinné extrakty MeSH