The effect is described of selenium supplemented in an inorganic and organic form on the innate immune response of goats. Though the phagocytic activity (as a marker of the immune function) was found to be lower in organic-Se-treated group than in control (54.5 +/- 4.32 vs. 60.2 +/- 9.15 %), it did not generally exhibit any significant differences; similarly, no differences were found in the phagocytic index. The production of reactive oxygen species (ROS) was determined using the luminol-enhanced chemiluminescence (CL) (estimated as peak CL, integral CL and a peak time after addition of calcium ionophore A23187, opsonised zymosan (OZP) and phorbol-12-myristate-13-acetate as effectors. A significant ROS increase reflected in integral CL and a peak time was found in the inorganic-Se-treated group when OZP was used as activator; other parameters did not exhibit significant changes. The supplementation of Se in inorganic form can thus be seen to influence positively the innate immune system of kids.

• MeSH
• Inorganic Chemicals administration & dosage   MeSH
• Phagocytosis drug effects   MeSH
• Immunologic Factors administration & dosage   MeSH
• Goats MeSH
• Organic Chemicals administration & dosage   MeSH
• Immunity, Innate drug effects   MeSH
• Reactive Oxygen Species metabolism   MeSH
• Selenium administration & dosage   MeSH
• Animals MeSH
• Check Tag
• Male MeSH
• Female MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH
• Names of Substances
• Inorganic Chemicals MeSH
• Immunologic Factors MeSH
• Organic Chemicals MeSH
• Reactive Oxygen Species MeSH
• Selenium MeSH