Re-differentiation of human articular chondrocytes is not enhanced by a rotary bioreactor system
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ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.
- MeSH
- agrekany metabolismus MeSH
- bioreaktory MeSH
- buněčná diferenciace * genetika MeSH
- buněčné kultury MeSH
- chondrocyty cytologie metabolismus transplantace MeSH
- exprese genu MeSH
- kloubní chrupavka cytologie metabolismus MeSH
- kolagen typ II metabolismus MeSH
- kolagen typu I metabolismus MeSH
- kultivované buňky MeSH
- lidé MeSH
- PEG-DMA hydrogel MeSH
- tkáňové inženýrství metody MeSH
- tkáňové podpůrné struktury MeSH
- versikany metabolismus MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Názvy látek
- agrekany MeSH
- kolagen typ II MeSH
- kolagen typu I MeSH
- PEG-DMA hydrogel MeSH
- versikany MeSH