The prevalence of right bundle branch block (RBBB) according to clinical findings was investigated in 4210 randomly selected subjects of both sexes, aged 35 to 54, in 1969 and after a period of three years (1972). Rheumatic heart disease and decreased forced vital capacity were more often found in persons with RBBB than in persons without RBBB. The prevalence of RBBB was 0.24% in 1969 and 0.35% in 1972. Incomplete RBBB (iRBBB) was found in 2.95% in 1969 and in 1.64% in 1972. The R1 smaller than the R wave in V1 or V2 was seen in 3.37% in 1969 and in 2.72% in 1972. RBBB remained constant over a period of three years, iRBBB was constant in 40.8% and R1 smaller than the R wave in V1/V2 was constant in 34.8%. Hypertension and depression of the S-T segment and inverted T wave before and after exercise were not more frequent in subjects with RBBB than in those without RBBB.

• MeSH
• Bundle-Branch Block complications   diagnosis   epidemiology   MeSH
• Adult MeSH
• Electrocardiography MeSH
• Middle Aged MeSH
• Humans MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Yugoslavia MeSH

BACKGROUND: Cardiac resynchronization therapy (CRT) improves symptoms of heart failure (HF), morbidity and mortality in selected population. The aim of the study was to investigate the impact of cardiac magnetic resonance (CMR)-guided left ventricular (LV) lead placement on clinical outcomes and LV reverse remodelling in CRT recipients. METHODS: Patients with CRT indication were randomized for CMR-guided (CMR group) or electrophysiologically guided (EP group) LV lead placement between 2011 and 2014. The target site in the CMR group was defined as the most delayed, scar-free, in the EP group as the site with the longest interval between the QRS onset and local electrogram. The primary endpoint was a combination of cardiovascular death or HF hospitalization. Secondary endpoints were New York Heart Association (NYHA) Class improvement ≥1, LV endsystolic diameter reduction >10%, B-type natriuretic peptide reduction by ≥30%. RESULTS: A total of 99 patients (47 in the CMR and 52 in the EP group) were enrolled. During a median follow-up of 47 months, primary composite endpoint occurred in 5 patients in the CMR group and 14 patients in the EP group (HR = 0.46; 95% CI: 0.16-1.32). Patients with left bundle branch block and NYHA Class >2 had better clinical outcome in the CMR group (HR = 0.09; 95% CI: 0.01-0.75). CONCLUSIONS: The use of CMR did not result in significant reduction of combined endpoint of cardiovascular death or HF hospitalization in the total study population. Significant clinical benefit from CMR-guided procedure was observed in a subgroup of optimum CRT candidates with advanced HF.

• Keywords
• Heart failure, Magnetic resonance, Resynchronization therapy, Target segment,
• MeSH
• Middle Aged MeSH
• Humans MeSH
• Magnetic Resonance Imaging, Cine methods   MeSH
• Follow-Up Studies MeSH
• Prospective Studies MeSH
• Aged MeSH
• Cardiac Resynchronization Therapy methods   MeSH
• Heart Failure diagnostic imaging   physiopathology   therapy   MeSH
• Treatment Outcome MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Randomized Controlled Trial MeSH