AIM: The aim of this paper is to present clinical experience with the therapy of retinal juxtapapillary hemangioma using the intravitreal application of anti-VEGF substance (bevacizumab) and photodynamic therapy (PDT) with verteporfine (Visudyne). MATERIAL AND METHODS: The authors present a case of a 34 years old male patient with diagnosed retinal hemangioma localized on the optic disc. Subjectively, the patient noticed decrease of vision, and during the clinical examination, the edema in the macula region spreading from the hemangioma with hard exsudates was found; the best-corrected visual acuity (BCVA) was 4/20 (0.2). RESULTS: First, the patient was treated by intravitreal applications of bevacizumab; after the first application, the edema from the macula subsided, and the best-corrected visual acuity improved to 4/12 (0.33). After one month of the first application, a recurrence of the edema occurred and other two injections of bevacizumab were applied; despite this treatment, further worsening of the exsudation from the hemangioma and worsening of the BCVA to 4/32 (0.125) occurred. Subsequently, one session of photodynamic therapy with verteporfine was held. After this therapy, the finding on the posterior ocular pole was stabilized; the BCVA was 4/40 (0.1). Even one year after the PDT therapy, no recurrence was present. CONCLUSION: According to our experience, the PDT with Visudyne appears as promising therapy method of juxtapapillary capillary hemangiomas. The PDT decreases the leaking of the fluid from hemangioma and decreases the size of hemangioma.

• MeSH
• bevacizumab MeSH
• dospělí MeSH
• fluoresceinová angiografie MeSH
• fotochemoterapie metody   MeSH
• fotosenzibilizující látky terapeutické užití   MeSH
• fundus oculi MeSH
• humanizované monoklonální protilátky terapeutické užití   MeSH
• inhibitory angiogeneze terapeutické užití   MeSH
• kapilární hemangiom diagnóza   farmakoterapie   MeSH
• kombinovaná farmakoterapie MeSH
• lidé MeSH
• nádory sítnice diagnóza   farmakoterapie   MeSH
• optická koherentní tomografie MeSH
• porfyriny terapeutické užití   MeSH
• vaskulární endoteliální růstový faktor A antagonisté a inhibitory   MeSH
• verteporfin MeSH
• zraková ostrost MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• kazuistiky MeSH
• Názvy látek
• bevacizumab MeSH
• fotosenzibilizující látky MeSH
• humanizované monoklonální protilátky MeSH
• inhibitory angiogeneze MeSH
• porfyriny MeSH
• vaskulární endoteliální růstový faktor A MeSH
• verteporfin MeSH