delusional disorder Dotaz Zobrazit nápovědu
BACKGROUND: Current research attention has been moving toward the needs of patients and their consequences for the quality of life (QoL). Self-stigma is a maladaptive psychosocial phenomenon disturbing the QoL in a substantial number of psychiatric patients. In our study, we examined the relationship between demographic data, the severity of symptoms, self-stigma, and QoL in patients with schizophrenia spectrum disorder. METHODS: Probands who met International Classification of Diseases-10 criteria for schizophrenia spectrum disorder (schizophrenia, schizoaffective disorder, or delusional disorder) were recruited in the study. We studied the correlations between the QoL measured by the QoL Satisfaction and Enjoyment Questionnaire, self-stigma assessed by the Internalized Stigma of Mental Illness, and severity of the disorder measured by the objective and subjective Clinical Global Impression severity scales in this cross-sectional study. RESULTS: A total of 109 psychotic patients and 91 healthy controls participated in the study. Compared with the control group, there was a lower QoL and a higher score of self-stigmatization in psychotic patients. We found the correlation between an overall rating of self-stigmatization, duration of disorder, and QoL. The level of self-stigmatization correlated positively with total symptom severity score and negatively with the QoL. Multiple regression analysis revealed that the overall rating of objective symptom severity and the score of self-stigma were significantly associated with the QoL. CONCLUSION: Our study suggests a negative impact of self-stigma level on the QoL in patients suffering from schizophrenia spectrum disorders.
- Klíčová slova
- delusional disorder, quality of life, schizoaffective disorder, schizophrenia, self-stigma,
- Publikační typ
- časopisecké články MeSH
A few case reports on the delusion of pregnancy can be found in the published literature. However, the delusion of maternity, a delusional conviction of the patient that she is a mother of one or more children, has not yet been studied closely. The author describes the case of a 62-year-old childless patient with a diagnosis of chronic paranoid schizophrenia. She developed a delusion of maternity, persistent for many years. This markedly influenced her behaviour.
- MeSH
- bludy * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mateřské chování psychologie MeSH
- paranoidní schizofrenie komplikace psychologie MeSH
- pseudogravidita psychologie MeSH
- těhotenství MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
We identified a potential neurophysiological marker for processing of verbal cues in paranoid schizophrenia: high desynchronization in the beta-2 band in the right parietal area for meaningless cues, and no synchronization differences in the beta-2 and gamma bands in the left prefrontal area pointing to deficient categorization of the stimuli.
- Klíčová slova
- desynchronization, electroencephalography (EEG), psychosis, schizoaffective disorder, schizophrenia, synchronization,
- MeSH
- elektroencefalografie MeSH
- emoce MeSH
- lidé MeSH
- paranoidní schizofrenie * MeSH
- podněty MeSH
- sémantika * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Klíčová slova
- PSYCHOSES *, SCHIZOPHRENIA/psychology *,
- MeSH
- lidé MeSH
- paranoidní schizofrenie * MeSH
- psychotické poruchy * MeSH
- schizofrenie (psychologie) * MeSH
- schizofrenie psychologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Klíčová slova
- PARANOIA *,
- MeSH
- lidé MeSH
- paranoidní poruchy * MeSH
- paranoidní schizofrenie * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
The authors examined 29 patients with endogenous psychosis (incl. 25 suffering from paranoid schizophrenia and four suffering from bipolar psychosis diagnosed according to DSM III criteria) with the aim to reveal the relationship of hitherto little studied HLA-DR antigens and the psychotic disease. Moreover, the passesed in the group also the ration of HLA-A, B, C antigens. In patients with paranoid schizophrenia and in all patients they found a higher incidence of HLA-DR2 antigens and a lower incidence of HLA-DRw6 and DR7. A statistically significant result was obtained only for HLA-DR2, and only before correction of p. The corrected p value (for the number of antigens) was no longer significant. This finding may serve as a stimulus to resolve the relationship of HLA-DR antigens and schizophrenia in a larger number of patients and in a greater number of departments.
- MeSH
- HLA-DR antigeny analýza MeSH
- lidé MeSH
- paranoidní poruchy imunologie MeSH
- paranoidní schizofrenie imunologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Názvy látek
- HLA-DR antigeny MeSH
- MeSH
- lidé MeSH
- paranoidní poruchy komplikace diagnóza MeSH
- paranoidní schizofrenie diagnóza MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Klíčová slova
- PSYCHOTHERAPY *, SCHIZOPHRENIA/therapy *,
- MeSH
- lidé MeSH
- paranoidní schizofrenie * MeSH
- psychoterapie * MeSH
- schizofrenie terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- ambulantní péče * MeSH
- anxiolytika terapeutické užití MeSH
- benzodiazepiny MeSH
- dibenzazepiny terapeutické užití MeSH
- elektroencefalografie MeSH
- lidé MeSH
- obsedantně kompulzivní porucha diagnóza farmakoterapie MeSH
- paranoidní poruchy diagnóza farmakoterapie MeSH
- paranoidní schizofrenie diagnóza farmakoterapie MeSH
- psychotické poruchy farmakoterapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- anxiolytika MeSH
- benzodiazepiny MeSH
- dibenzazepiny MeSH