Expert academic and pharmaceutical researchers describe their best capillary electrophoresis techniques for protein and peptide analysis. The authors present cutting-edge techniques for both capillary coatings and analytic detection via laser-induced fluorescence, for the development and commercialization of biopharmaceuticals, and for affinity capillary electrophoresis in the evaluation of protein binding, including the use of protein charge ladders. Areas of special interest covered include combining CE and capillary isoelectric focusing with electrospray mass spectrometry detection to perform proteomic studies and applications in the field of protein-ligand binding.

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Surfactant based methods for prevention of protein adsorption in capillary electrophoresis / Charles A. Lucy, Nicole E. Baryla, and Ken K.-C. Yeung -- Capillary coating for protein separation based on Si-O and Si-C covalent bond formation for capillary electrophoresis with laser-induced fluorescence detection / Hossein Ahmadzadeh, Norman J. Dovichi, and Sergey Krylov -- On-column labeling reaction for the analysis of protein contents of a single cell using capillary electrophoresis with laser-induced fluorescence detection / Hossein Ahmadzadeh and Sergey Krylov --