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Re-differentiation of human articular chondrocytes is not enhanced by a rotary bioreactor system
Barlič A, Kregar-Velikonja N.
Jazyk angličtina Země Česko
NLK
Free Medical Journals
od 2000
Freely Accessible Science Journals
od 2000
ProQuest Central
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2000
- MeSH
- agrekany metabolismus MeSH
- bioreaktory MeSH
- buněčná diferenciace genetika MeSH
- buněčné kultury MeSH
- chondrocyty cytologie metabolismus transplantace MeSH
- exprese genu MeSH
- kloubní chrupavka cytologie metabolismus MeSH
- kolagen typ II metabolismus MeSH
- kolagen typu I metabolismus MeSH
- kultivované buňky MeSH
- lidé MeSH
- PEG-DMA hydrogel MeSH
- tkáňové inženýrství metody MeSH
- tkáňové podpůrné struktury MeSH
- versikany metabolismus MeSH
- Check Tag
- lidé MeSH
ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating- wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.
Lit.: 12
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- $a ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating- wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.
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