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Recent advances in the research on biological roles of dietary polyamines in man
Pavel Kalač
Language English Country Czech Republic
Document type Tables, Review
NLK
Free Medical Journals
from 2003 to 2013
Freely Accessible Science Journals
from 2003 to 2013
ROAD: Directory of Open Access Scholarly Resources
from 2002
- MeSH
- Food Analysis methods statistics & numerical data MeSH
- Antioxidants isolation & purification metabolism MeSH
- Biomedical Research methods trends MeSH
- Cell Growth Processes immunology drug effects MeSH
- Dietetics methods trends MeSH
- Financing, Organized MeSH
- Gastrointestinal Tract metabolism drug effects MeSH
- Wound Healing immunology drug effects MeSH
- Humans MeSH
- Neoplasms diet therapy prevention & control MeSH
- Polyamines isolation & purification metabolism toxicity MeSH
- Putrescine isolation & purification metabolism MeSH
- Spermidine isolation & purification metabolism MeSH
- Spermine isolation & purification metabolism MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
- Tables MeSH
The ubiquitous polyamines putrescine, spermidine and spermine fulfil an array of physiological roles in man. In particular, their participation in cell growth and proliferation has been of great interest in relation to their roles in tumour growth and in wound healing. Both endogenous and dietary polyamines take part in such processes. The deprivation of exogenous polyamines emerges as a promising strategy in tumour therapy. Thus, reliable information on their content in foods is needed for dieticians. This review continues our previous comprehensive review on the topic,summarising data on the polyamine content in foods published from 2005 to April 2009. Some new data has appeared. Bovine, porcine and chicken liver, kidney, spleen and heart all have a high content of spermine; bovine liver also of spermidine. Losses of spermidine and spermine up to one half of their original levels occur during both cold and frozen storage and during various thermal treatments. Cultivated mushrooms were reported to contain very high levels of spermidine. Recent results have proved that polyamine content varies widely within a food item, and this complicates the application of available data for the controlled nutrition of patients.
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Lit.: 56
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- $a The ubiquitous polyamines putrescine, spermidine and spermine fulfil an array of physiological roles in man. In particular, their participation in cell growth and proliferation has been of great interest in relation to their roles in tumour growth and in wound healing. Both endogenous and dietary polyamines take part in such processes. The deprivation of exogenous polyamines emerges as a promising strategy in tumour therapy. Thus, reliable information on their content in foods is needed for dieticians. This review continues our previous comprehensive review on the topic,summarising data on the polyamine content in foods published from 2005 to April 2009. Some new data has appeared. Bovine, porcine and chicken liver, kidney, spleen and heart all have a high content of spermine; bovine liver also of spermidine. Losses of spermidine and spermine up to one half of their original levels occur during both cold and frozen storage and during various thermal treatments. Cultivated mushrooms were reported to contain very high levels of spermidine. Recent results have proved that polyamine content varies widely within a food item, and this complicates the application of available data for the controlled nutrition of patients.
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