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Hirtusneanoside, an unsymmetrical dimeric tetrahydroxanthone from the lichen Usnea hirta
T Rezanka, K Sigler
Language English Country United States
- MeSH
- Anti-Bacterial Agents pharmacology chemistry isolation & purification MeSH
- Bacillus subtilis drug effects MeSH
- Financing, Organized MeSH
- Glycosides pharmacology chemistry isolation & purification MeSH
- Molecular Structure MeSH
- Nuclear Magnetic Resonance, Biomolecular MeSH
- Staphylococcus aureus drug effects MeSH
- Usnea chemistry MeSH
- Xanthones pharmacology chemistry isolation & purification MeSH
- Geographicals
- Czech Republic MeSH
Hirtusneanoside, a new O-deoxyglycoside of a dimeric tetrahydroxanthone, was isolated from the lichen Usnea hirta. Its structure, including the absolute configuration, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, 1D and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure comprising L-rhamnopyranoside of a tetrahydroxanthone dimer and showed growth inhibitory activities against Gram-positive bacteria.
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- $a Institute of Microbiology, Prague, Czech Republic. rezanka@biomed.cas.cz
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- $a Hirtusneanoside, a new O-deoxyglycoside of a dimeric tetrahydroxanthone, was isolated from the lichen Usnea hirta. Its structure, including the absolute configuration, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, 1D and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure comprising L-rhamnopyranoside of a tetrahydroxanthone dimer and showed growth inhibitory activities against Gram-positive bacteria.
- 650 _2
- $a antibakteriální látky $x farmakologie $x chemie $x izolace a purifikace $7 D000900
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- $a Bacillus subtilis $x účinky léků $7 D001412
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- $a glykosidy $x farmakologie $x chemie $x izolace a purifikace $7 D006027
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- $a nukleární magnetická rezonance biomolekulární $7 D019906
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- $a Staphylococcus aureus $x účinky léků $7 D013211
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- $a Usnea $x chemie $7 D020949
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- $a xantony $x farmakologie $x chemie $x izolace a purifikace $7 D044004
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- $a financování organizované $7 D005381
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- $a Česká republika $7 D018153
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- $a Sigler, Karel, $d 1942- $7 xx0102701
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- $t Journal of Natural Products $w MED00010055 $g Roč. 70, č. 9 Sep (2007), s. 1487-1491 $x 0163-3864
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