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Effect of mineral water from Trenčianske Teplice (drinkable source, Drill SB-3) on lipid peroxidation in vitro
Ďurfinová M., Brechtlová M., Kuračka Ľ., Zálešáková J., Čelko J., Líška B.
Language English Country Czech Republic
- MeSH
- Financing, Organized MeSH
- Rats MeSH
- Thiobarbituric Acid Reactive Substances metabolism MeSH
- Mineral Waters MeSH
- Brain metabolism MeSH
- Lipid Peroxidation drug effects MeSH
- Rats, Wistar MeSH
- Iron pharmacology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
Influence of mineral water from Trenčianske Teplice (drinkable source) on lipid peroxidation processes was determined in model situations under in vitro conditions using the brain tissue. The central nervous system was selected because it is especially sensitive to the radical-induced damage. In addition, there is a high content of polyunsaturated fatty acids in the brain which has a low antioxidant capacity and is relatively rich in iron ions – enhancers of lipid peroxidation processes. We present the inhibitory effect of the mineral water on the intensity of lipid peroxidation in the presence of iron ions. We assume that some component or combination of more components of the mineral water may act as chelators of iron ions.
Lit.: 10
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- $a Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Bratislava
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- $a Lit.: 10
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- $a Influence of mineral water from Trenčianske Teplice (drinkable source) on lipid peroxidation processes was determined in model situations under in vitro conditions using the brain tissue. The central nervous system was selected because it is especially sensitive to the radical-induced damage. In addition, there is a high content of polyunsaturated fatty acids in the brain which has a low antioxidant capacity and is relatively rich in iron ions – enhancers of lipid peroxidation processes. We present the inhibitory effect of the mineral water on the intensity of lipid peroxidation in the presence of iron ions. We assume that some component or combination of more components of the mineral water may act as chelators of iron ions.
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- $a mozek $x metabolismus $7 D001921
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