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Personalized chronobiologic cybercare; other chronomics' progress by transdisciplinary cycles' congruences: season's appreciations 2009
Franz Halberg, Germaine Cornelissen, Patricia Grambsch, Rollin McCraty, Larry Beaty, Jarmila Siegelova, Pavel Homolka, Dewayne Carol Hillman, Judy Finley, Faithe Thomas, Tomoshige Kino, Miguel Revilla, Othild Schwartzkopff
Language English Country Czech Republic
Document type Review
NLK
Free Medical Journals
from 2003 to 2013
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ROAD: Directory of Open Access Scholarly Resources
from 2002
- MeSH
- Biological Clocks MeSH
- Chronobiology Discipline methods trends MeSH
- Chronotherapy methods standards utilization MeSH
- Circadian Rhythm MeSH
- Financing, Organized MeSH
- Cardiovascular Diseases prevention & control MeSH
- Drug Chronotherapy MeSH
- Humans MeSH
- Blood Pressure Determination MeSH
- Neoplasms therapy MeSH
- Death, Sudden, Cardiac prevention & control MeSH
- Periodicity MeSH
- Suicide Prevention MeSH
- Reference Standards MeSH
- Suicide MeSH
- Heart Rate MeSH
- Statistics as Topic MeSH
- Terrorism prevention & control MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Originally a remembrance of an elderly physiologist, this paper illustrates the need for a standardized specification of certain experimental or survey conditions beyond those usually necessarily disclosed in conventional publications, namely calendar-dates, clock-times and geographic locations, to allow reference to helio-ionosphero-geomagnetics along with natural and artificial lighting and temperature. When possible, body times given by a marker rhythm also should be specified. A personalized chronobiologic cybercare can eventually include focus on infradians, beyond circadians. Benefits from longitudinal monitoring are: 1. Chronobiologically-interpreted blood pressure (BP) and heart rate (HR) monitoring enables the diagnosis and treatment of Vascular Variability Anomalies (VVAs) or, if lasting in several 7-day records, Disorders (VVDs), not yet screened for in practice, that increase cardiovascular disease risk independently of an elevated BP. 2. The optimal treatment time for the individual patient can be determined and potential harm avoided, since the same dose of the same medication for the same patient can help or harm depending only on when it is administered. 3. Benefit may be derived in cancer treatment timed according to marker rhythmometry. 4. The change from a spotcheck-based health care to one of internet-aided systematic self-surveillance by the automatic collection and analysis of time series stems from evidence that nonphotic and photic environmental influences affect biota, associations that may depend on geographic and temporal location. 5. Imaging in time includes formatting for time, globally and locally, for the mapping of a transdisciplinary spectrum of cycles involving "good" and "bad" strain in human physiology, versus sudden cardiac death, suicide and terrorism, all latter requiring rational countermeasures.
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Lit.: 104
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