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Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage
M Davidkova, P Kundrat, V Stepan, Z Palajova, L Judas
Applied radiation and isotopes.
2009 ;
67 (3) :
454-459.
Jazyk angličtina Země Velká Británie
Perzistentní odkaz
https://www.medvik.cz/link/bmc11006091
- MeSH
- buněčné linie MeSH
- buňky účinky záření MeSH
- financování organizované MeSH
- lidé MeSH
- poškození DNA účinky záření MeSH
- protony MeSH
- viabilita buněk účinky záření MeSH
- vztah dávky záření a odpovědi MeSH
- Check Tag
- lidé MeSH
Published survival data of V79 cells irradiated by 0.5-5.0 MeV (7-40 keV/microm) protons have been analyzed with a detailed radiobiological model to estimate the per-track yields of lethal lesions. Their correlations with distribution patterns of deposited energy, radical concentrations and with the yields of specific classes of DNA damage have been studied. The observed correlations indicate a potential interpretation of DNA damage lethal for the cell and the initial physical and chemical processes leading to such damage.
Citace poskytuje Crossref.org
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