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Surprisingly delayed escalation of severe verapamil poisoning
V. Tuka, B. Říčařová, T. Janota, J. Malík, E. Kotrlíková
Jazyk angličtina Země Velká Británie
Typ dokumentu kazuistiky
- MeSH
- blokátory kalciových kanálů otrava MeSH
- hypotenze diagnóza chemicky indukované MeSH
- kóma chemicky indukované MeSH
- léky s prodlouženým účinkem otrava MeSH
- lidé MeSH
- měření krevního tlaku MeSH
- pokus o sebevraždu MeSH
- senioři MeSH
- verapamil otrava MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
We present a case report of intoxication by a potentially lethal dose of sustained-release verapamil with delayed escalation of complications. The patient was hospitalized 1.5 h after an attempted suicide with a very high dose of verapamil sustained-release (7.2 g). On admission the plasma concentrations were extremely high (3600 ng/l). Heart rate and blood pressure declined slowly with a surprising sudden escalation on the third day coupled with hemodynamic collapse and loss of consciousness. Complete recovery was achieved in spite of 2 h of extreme hypotension. We outline the clinical course, a need for massive bowel irrigation in case of sustained-release medication, the timing of a temporary pacing and the effect of centralization of circulation even on invasively measured blood pressure.
Citace poskytuje Crossref.org
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