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Survival and infertility treatment in male cancer patients after sperm banking
I. Crha, P .Ventruba, J. Žáková, M. Huser, B. Kubešová, R. Hudeček, J. Jarkovský
Jazyk angličtina Země Spojené státy americké
Typ dokumentu práce podpořená grantem
NLK
ScienceDirect (archiv)
od 1993-01-01 do 2009-12-31
- MeSH
- azoospermie MeSH
- časové faktory MeSH
- intracytoplazmatické injekce spermie MeSH
- kryoprezervace metody MeSH
- lidé MeSH
- mužská infertilita terapie MeSH
- nádory chirurgie MeSH
- novorozenec MeSH
- retrospektivní studie MeSH
- sperma MeSH
- spermabanky metody MeSH
- těhotenství MeSH
- testikulární nádory chirurgie mortalita MeSH
- uchování spermatu metody MeSH
- vedení porodu MeSH
- zmrazování MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- práce podpořená grantem MeSH
OBJECTIVE: To evaluate the relationship between sperm pathology and cancer diagnosis, determine the mortality rate, and evaluate the outcomes of the use of frozen sperm from the sperm bank. DESIGN: Prospective study. SETTING: University fertility center. PATIENT(S): A total of 619 male patients were referred for sperm freezing before gonadotoxic therapy from 1995 to 2006. INTERVENTION(S): Semen analysis, data verification in the National Oncologic Register, assisted reproduction technologies, and statistical evaluation. MAIN OUTCOME MEASURE(S): Cancer diagnosis and sperm pathology analysis, survival of patients, and infertility treatment success. RESULT(S): Malignant testicular cancer was diagnosed in 43.6% of patients, and malignant neoplasms of the lymphatic and hematopoietic tissues were found in 31.7% of patients. Azoospermia or severe oligospermia (
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- $a Crha, Igor, $d 1955- $7 jn20001005240
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- $a Survival and infertility treatment in male cancer patients after sperm banking / $c I. Crha, P .Ventruba, J. Žáková, M. Huser, B. Kubešová, R. Hudeček, J. Jarkovský
- 314 __
- $a Department of Gynecology and Obstetrics, Faculty of Medicine, Masaryk University, Faculty Hospital, Brno, Czech Republic. icrha@seznam.cz
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- $a OBJECTIVE: To evaluate the relationship between sperm pathology and cancer diagnosis, determine the mortality rate, and evaluate the outcomes of the use of frozen sperm from the sperm bank. DESIGN: Prospective study. SETTING: University fertility center. PATIENT(S): A total of 619 male patients were referred for sperm freezing before gonadotoxic therapy from 1995 to 2006. INTERVENTION(S): Semen analysis, data verification in the National Oncologic Register, assisted reproduction technologies, and statistical evaluation. MAIN OUTCOME MEASURE(S): Cancer diagnosis and sperm pathology analysis, survival of patients, and infertility treatment success. RESULT(S): Malignant testicular cancer was diagnosed in 43.6% of patients, and malignant neoplasms of the lymphatic and hematopoietic tissues were found in 31.7% of patients. Azoospermia or severe oligospermia (<or=1 million/mL) was detected in 9.7% and 22.6% of patients, respectively. To date, 32 patients (5.2%) sought infertility treatment. Cryopreserved semen was used in 28 couples (87.5%), and 44 intracytoplasmic sperm injection (ICSI) cycles resulted in 13 pregnancies. In total, 74 deaths (11.9%) were reported, 61 of them (82.4%) within 30 months of the cryopreservation of their sperm. CONCLUSION(S): A significant number of patients survived. Intrauterine insemination and ICSI with cryopreserved sperm resulted in deliveries.
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- $a uchování spermatu $x metody $7 D012662
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- $a intracytoplazmatické injekce spermie $7 D020554
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- $a testikulární nádory $x chirurgie $x mortalita $7 D013736
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- $a Ventruba, Pavel, $d 1954- $7 jn20000402510
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- $t Fertility & Sterility $w MED00001795 $g Roč. 91, č. 6 (2009), s. 2344-2348
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- $a 2011-3B09/Bjvme
