Aim Assessment of the left ventricle diastolic function in a group of patients with stable coronary artery disease and regular physical training. Methods The study included thirty patients with stable coronary artery disease. Every patient had participated in the conducted 3-moth physical training in Department of Functional Diagnostic and Rehabilitation St. Anna Hospital. After one year the patients were retrospectively divided into two cohorts according to their physical activity. The patients in cohort C (consisting of 14 patients) continued in aerobic physical training after the end of the rehabilitation programme. The patients in cohort N (consisting of 16 patients) had stopped their training after finishing the conducted programme in St. Anne’s Faculty Hospital. The peak diastolic velocities of myocardial motion were measured at individual LV walls: septum, lateral, anterior, and inferior walls. In addition, to determine global LV diastolic function, the four-site mean diastolic velocity was calculated (Ea glob, Ea/Aa glob). The velocities were evaluated at rest and at the maximal load. According to blood supply, left ventricular walls were divided into five groups: 0 – walls supplied by non-stenotic artery; 1 – walls supplied by artery with coronary stenosis ? 50 %; 2 – walls supplied by artery with stenosis 51–70 %; 3 – walls with stenosis of supplying artery 71–99 %; 4 – walls with totally occluded supplying artery. For every patient the difference between the values Ea and Ea/Aa for each wall at the end of the study and the values at the beginning of the study was assessed. The values of the particular walls were divided into.

1st Department of Internal Medicine Cardioangiology St Anne's Faculty Hospital Masaryk University ICRC Brno

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