Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Mechanical properties of mitral allografts are not reasonably influenced by cryopreservation in sheep model

J. Hlubocký, A. Mokráček, V. Nováček, J. Vojáček, J. Burkert, P. Kochová, J. Klepáček, J. Pepper, J. Špatenka

. 2011 ; 60 (3) : 475-482.

Jazyk angličtina Země Česko

Perzistentní odkaz   https://www.medvik.cz/link/bmc11032044

A mitral allograft is used exceptionally in the mitral, as well as in the tricuspid position, mostly as an experimental surgical procedure. The authors decided to evaluate the possibility of inserting a cryopreserved mitral allograft into the tricuspid position in a sheep experimental model. Within the framework of this experimental project the mechanical properties of the cryopreserved mitral allograft were tested. A novel methodology studying the functional unit composed of mitral annulus, leaflet, chordae tendinaea, and papillary muscle is presented. A five-parameter Maxwell model was applied to characterize the viscoelastic behavior of sheep mitral valves. A control group of 39 fresh mitral specimens and a test group of 13 cryopreserved mitral allografts from tissue bank were tested. The testing protocol consisted of six loading cycles with 1 mm elongation every 5 min. There was no significant difference in the mean values of the determined parameters (p>0.05) which confirms the main hypothesis that cryopreservation does not influence significantly material parameters characterizing the tissue mechanics. Slight discrepancy is observed in variances of viscous parameters suggesting that the values of the test group may be spread over larger interval due to the treatment.

Citace poskytuje Crossref.org

Bibliografie atd.

Lit.: 19

000      
00000naa 2200000 a 4500
001      
bmc11032044
003      
CZ-PrNML
005      
20120328092952.0
008      
110912s2011 xr e eng||
009      
AR
024    7_
$a 10.33549/physiolres.932074 $2 doi
035    __
$a (PubMed)21401294
040    __
$a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Hlubocký, Jaroslav $7 xx0074061
245    10
$a Mechanical properties of mitral allografts are not reasonably influenced by cryopreservation in sheep model / $c J. Hlubocký, A. Mokráček, V. Nováček, J. Vojáček, J. Burkert, P. Kochová, J. Klepáček, J. Pepper, J. Špatenka
314    __
$a Transplant Center University Hospital Motol, Prague, Czech Republic. vit.novacek@gmail.com.
504    __
$a Lit.: 19
520    9_
$a A mitral allograft is used exceptionally in the mitral, as well as in the tricuspid position, mostly as an experimental surgical procedure. The authors decided to evaluate the possibility of inserting a cryopreserved mitral allograft into the tricuspid position in a sheep experimental model. Within the framework of this experimental project the mechanical properties of the cryopreserved mitral allograft were tested. A novel methodology studying the functional unit composed of mitral annulus, leaflet, chordae tendinaea, and papillary muscle is presented. A five-parameter Maxwell model was applied to characterize the viscoelastic behavior of sheep mitral valves. A control group of 39 fresh mitral specimens and a test group of 13 cryopreserved mitral allografts from tissue bank were tested. The testing protocol consisted of six loading cycles with 1 mm elongation every 5 min. There was no significant difference in the mean values of the determined parameters (p>0.05) which confirms the main hypothesis that cryopreservation does not influence significantly material parameters characterizing the tissue mechanics. Slight discrepancy is observed in variances of viscous parameters suggesting that the values of the test group may be spread over larger interval due to the treatment.
650    02
$a zvířata $7 D000818
650    02
$a kryoprezervace $7 D015925
650    02
$a srdeční chlopně umělé $7 D006350
650    02
$a mitrální chlopeň $7 D008943
650    02
$a modely u zvířat $7 D023421
650    02
$a ovce $7 D012756
650    02
$a mechanický stres $7 D013314
650    02
$a povrchové vlastnosti $7 D013499
650    02
$a trikuspidální chlopeň $x chirurgie $7 D014261
700    1_
$a Mokráček, Aleš, $d 1966- $7 xx0094268
700    1_
$a Nováček, Vít. $7 xx0244659
700    1_
$a Vojáček, Jan, $d 1967- $7 xx0080226
700    1_
$a Burkert, Jan $7 xx0171077
700    1_
$a Kochová, Petra. $7 _AN047718
700    1_
$a Klepáček, Jan. $7 _AN062876
700    1_
$a Pepper, J.
700    1_
$a Špatenka, Jaroslav, $d 1945- $7 jn20000402869
773    0_
$w MED00003824 $t Physiological research $g Roč. 60, č. 3 (2011), s. 475-482 $x 0862-8408
856    41
$u http://www.biomed.cas.cz/physiolres/pdf/60/60_475.pdf $y plný text volně přístupný
910    __
$a ABA008 $b A 4120 $c 266 $y 2
990    __
$a 20110912095705 $b ABA008
991    __
$a 20120328092935 $b ABA008
999    __
$a ok $b bmc $g 877124 $s 742121
BAS    __
$a 3
BMC    __
$a 2011 $b 60 $c 3 $d 475-482 $m Physiological research $x MED00003824
LZP    __
$a 2011-16/mkme

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé