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Use of bio-degradable stents for the treatment of refractory benign gastrointestinal stenoses
Stanislav Rejchrt, Jan Bureš, Jan Brožík, Marcela Kopáčová
Language English Country Czech Republic
Document type Research Support, Non-U.S. Gov't
Digital library NLK
Full text - Article
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- MeSH
- Biocompatible Materials MeSH
- Crohn Disease surgery complications MeSH
- Adult MeSH
- Endoscopy, Gastrointestinal MeSH
- Humans MeSH
- Polymers MeSH
- Stents MeSH
- Intestinal Obstruction MeSH
- Absorbable Implants MeSH
- Animals MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
Bio-degradable stents are be made of different synthetic polymers (like polylactide or polyglycolide) or their co-polymers (polydioxanone). They can be used for treating benign stenoses of the small and large intestine, particularly in Crohn's disease. Endoscopic introduction of bio-degradable stents into small and large intestinal stenoses is feasible and relatively simple. Initial results are encouraging and the complication rate is low. However, there are still some difficulties that need to be overcome. The rate of early stent migration is still rather high (up to one third of patients). This might be solved by changes in the shape or rigidity of the stents as well as by further improvement in the design. Proof of long-term efficacy and safety requires further studies.
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Literatura
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