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Ascertainment of variations in the biological half-lives of bromide and sodium ions in the rat by in vivo gamma-ray measurement of 82Br and 24Na radionuclides

S Pavelka, M Vobecky, A Babicky

. 2009 ; 67 (12) : 2110-2112.

Language English Country Great Britain

Document type Research Support, Non-U.S. Gov't

With the aid of in vivo whole-body counting of the rats (administered simultaneously with the radionuclides (82)Br and (24)Na) by high-resolution gamma-ray spectrometry, we extended the applicability of our experimentally proved hypothesis that the biological half-life of bromide depends on the magnitude of sodium intake rather than on the intake of chloride, as was generally assumed. Variations in the biological half-life of bromide, as a substitute for sodium, were investigated in animals situated in very different physiological states, as regards their metabolic activity.

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