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Failure of noninvasive prediction of pulmonary hypertension in patients with idiopathic pulmonary fibrosis
F. Salajka, V. Bartos, J. Novosad, J. St'ásek, J. Bis, M. Brtko, P. Polanský, V. Koblízek, V. Sedlák,
Jazyk angličtina Země Itálie
Typ dokumentu časopisecké články
NLK
Directory of Open Access Journals
od 2004
ROAD: Directory of Open Access Scholarly Resources
od 2004 do 2016
ROAD: Directory of Open Access Scholarly Resources
od 2004 do 2016
PubMed
22428220
DOI
10.4081/monaldi.2011.218
Knihovny.cz E-zdroje
- MeSH
- lidé středního věku MeSH
- lidé MeSH
- plicní fibróza komplikace patofyziologie MeSH
- plicní hypertenze diagnóza etiologie patofyziologie ultrasonografie MeSH
- prognóza MeSH
- prospektivní studie MeSH
- reprodukovatelnost výsledků MeSH
- respirační funkční testy MeSH
- senioři MeSH
- senzitivita a specificita MeSH
- srdeční katetrizace MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Pulmonary hypertension (PH) in patients with advanced idiopathic pulmonary fibrosis (IPF) is a complication connected with unfavorable prognosis. Great efforts have been made in attempting to establish a reliable non-invasive method which would enable detection of this complication. In this context a formula using pulmonary function parameters was published with outstanding results. METHODS: We tested the formula in 27 IPF patients who underwent a lung function examination, cardiac ultrasonography and catheterisation on the same day. RESULTS: Pulmonary hypertension was detected by catheterisation in 17 patients (63%). In our group, contrary to the published data, the aforementioned formula was neither useful for detecting patients with a high probability of PH nor as a means of calculating the mean pulmonary artery pressure in individual patients (p = 0.502 and p = 0.833, respectively). Ultrasound examination reached borderline correlation with the values measured by catheterisation when we compare patients with relevant results (r = 0.531, p = 0.051). However, the examination gave no usable results in 13 patients (48%). CONCLUSION: Our data suggests that no reliable, noninvasive method is currently available for detecting and confirming PH in IPF patients. We did not confirm the usefulness of the published formula. Further carefully organised studies will be necessary to verify or refute it.
Citace poskytuje Crossref.org
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