Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.

Anotace

specifics are also available

DUI

D017451 MeSH Prohlížeč

CUI

M0026477

Předchozí užití

Receptors, Endogenous Substances (1980-1992); Receptors, Insulin (1980-1989)

Historická pozn.

93; was INSULIN-LIKE GROWTH FACTOR RECEPTOR (NM) 1980-92; INSULIN-LIKE GROWTH FACTORS RECEPTORS was see RECEPTORS, SOMATOMEDIN 1993

Online pozn.

use RECEPTORS, SOMATOMEDIN (NM) to search INSULIN-LIKE GROWTH FACTOR RECEPTOR 1980-92; use RECEPTORS, SOMATOMEDIN to search INSULIN-LIKE GROWTH FACTORS RECEPTOR 1993

Veřejná pozn.

93; INSULIN-LIKE GROWTH FACTOR RECEPTOR was indexed under RECEPTORS, ENDOGENOUS SUBSTANCES 1980-92 & RECEPTORS, INSULIN 1980-89; INSULIN-LIKE GROWTH FACTORS RECEPTORS was see RECEPTORS, SOMATOMEDIN 1993