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N-Benzylsalicylthioamides as novel compounds with promising antimycotic activity
E. Petrlíková, K. Waisser, V. Buchta, P. Jílek, M. Vejsová,
Bioorganic & medicinal chemistry letters.
2010 ;
20 (15) :
4535-8.
[pub] 20100611
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
Perzistentní odkaz
https://www.medvik.cz/link/bmc12026304
- MeSH
- antifungální látky chemie farmakologie MeSH
- flukonazol farmakologie MeSH
- kvantitativní vztahy mezi strukturou a aktivitou MeSH
- mikrobiální testy citlivosti MeSH
- thioamidy chemie farmakologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The in vitro biological activity of N-benzylsalicylthioamides was evaluated against eight fungal strains by the broth microdilution method and the results were compared with those obtained with fluconazole. The compounds exhibited an in vitro antifungal activity against the fluconazole-susceptible as well as the fluconazole-resistant fungal strains. The biological activity was analyzed by quantitative structure-activity relationship (QSAR).
Citace poskytuje Crossref.org
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