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A new biological test utilising the yeast Saccharomyces cerevisiae for the rapid detection of toxic substances in water
L. Rumlova, J. Dolezalova,
Language English Country Netherlands
Document type Journal Article
- MeSH
- Atropine analysis toxicity MeSH
- Water Pollutants, Chemical analysis toxicity MeSH
- Mercuric Chloride analysis toxicity MeSH
- Nitrates analysis toxicity MeSH
- Fenitrothion analysis toxicity MeSH
- Potassium Cyanide analysis toxicity MeSH
- Methylene Blue metabolism MeSH
- Environmental Monitoring methods MeSH
- Hazardous Substances analysis toxicity MeSH
- Lead analysis toxicity MeSH
- Saccharomyces cerevisiae drug effects metabolism MeSH
- Toxicity Tests methods MeSH
- Publication type
- Journal Article MeSH
This study evaluates the toxic effects of five substances (atropine, fenitrothion, potassium cyanide, mercuric chloride and lead nitrate) on the yeast Saccharomyces cerevisiae. It describes a new biological toxicity test based on inhibition of S. cerevisiae viability and compares it with two standard toxicity tests based on Daphnia magna mobility inhibition (EN ISO 6341) and Vibrio fischeri bioluminiscence inhibition (EN ISO 11348-2). The new biological test -S. cerevisiae lethal test - is cheaper and 24 times faster than the D. magna test. The test speed is comparable with the V. fischeri test but the new test is more sensitive for some substances. The test indicates reliably the presence of all used toxicants in water in concentrations which are significantly lower than the concentration in toxic or lethal doses for man. Therefore, this new toxicity test could be proposed for rapid detection of toxic substances in water.
References provided by Crossref.org
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- $a This study evaluates the toxic effects of five substances (atropine, fenitrothion, potassium cyanide, mercuric chloride and lead nitrate) on the yeast Saccharomyces cerevisiae. It describes a new biological toxicity test based on inhibition of S. cerevisiae viability and compares it with two standard toxicity tests based on Daphnia magna mobility inhibition (EN ISO 6341) and Vibrio fischeri bioluminiscence inhibition (EN ISO 11348-2). The new biological test -S. cerevisiae lethal test - is cheaper and 24 times faster than the D. magna test. The test speed is comparable with the V. fischeri test but the new test is more sensitive for some substances. The test indicates reliably the presence of all used toxicants in water in concentrations which are significantly lower than the concentration in toxic or lethal doses for man. Therefore, this new toxicity test could be proposed for rapid detection of toxic substances in water.
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