-
Je něco špatně v tomto záznamu ?
The impact of lower induction values of 50 Hz external electromagnetic fields on in vitro T lymphocyte adherence capabilities
A. Coček, A. Hahn, J. Mártonová, M. Ambruš, A. Dohnalová, M. Nedbalová, A. Jandová,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články
- MeSH
- buněčná adheze účinky záření MeSH
- dospělí MeSH
- elektromagnetická pole MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- nádory hltanu imunologie MeSH
- nádory hrtanu imunologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- T-lymfocyty cytologie účinky záření MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Our research thus far has concerned the impact of external electromagnetic fields (50 Hz) and low (0.01-10 mT) induction on adherence capabilities of T lymphocytes obtained from the blood of patients with head and neck tumors. We know that the in vitro adherence capability of T lymphocytes towards surfaces in cancer patients is less than that of control. Previously, we have found that exposure to electromagnetic fields (50 Hz/0.01-10 mT) increases the capability of T lymphocytes, in larynx/pharynx cancer patients, to adhere in vitro to surfaces, achieving almost physiological values, in not only pre-treatment patients but also those receiving treatment in the course of follow-up. The capability of T lymphocytes in controls (voluntary blood donors) to adhere to surfaces was also increased (50 Hz/0.01-0.5 mT). The present study concentrates on the significance of the level of electromagnetic field induction in order to determine whether low induction values can restore T lymphocytes adherence capabilities. Testing a subset of 20 patients showed a statistically significant difference (p<0.05) in the in vitro adherence capacity of T lymphocytes between both 0.01 and 0.05, and 0.1 mT induction levels. In the control group (patients diagnosed with chronic sensorineural hearing loss) there was even a statistically significant difference between induction values of 0.05 and 0.01 mT. A statistically significant difference (p<0.05) was also achieved with induction levels of 1 and 10 mT compared to 0.5, 0.1, and 0.05 mT, respectively. Therefore, we concluded that lower induction values resulted in a more biologically significant response.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc13000968
- 003
- CZ-PrNML
- 005
- 20220203082613.0
- 007
- ta
- 008
- 130108s2012 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3109/15368378.2011.630119 $2 doi
- 035 __
- $a (PubMed)22268989
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Coček, Aleš $u 3rd Faculty of Medicine, Charles University in Prague, Department of Otorhinolaryngology, Faculty Hospital Královské Vinohrady, Prague, Czech Republic. ales.cocek@seznam.cz
- 245 14
- $a The impact of lower induction values of 50 Hz external electromagnetic fields on in vitro T lymphocyte adherence capabilities / $c A. Coček, A. Hahn, J. Mártonová, M. Ambruš, A. Dohnalová, M. Nedbalová, A. Jandová,
- 520 9_
- $a Our research thus far has concerned the impact of external electromagnetic fields (50 Hz) and low (0.01-10 mT) induction on adherence capabilities of T lymphocytes obtained from the blood of patients with head and neck tumors. We know that the in vitro adherence capability of T lymphocytes towards surfaces in cancer patients is less than that of control. Previously, we have found that exposure to electromagnetic fields (50 Hz/0.01-10 mT) increases the capability of T lymphocytes, in larynx/pharynx cancer patients, to adhere in vitro to surfaces, achieving almost physiological values, in not only pre-treatment patients but also those receiving treatment in the course of follow-up. The capability of T lymphocytes in controls (voluntary blood donors) to adhere to surfaces was also increased (50 Hz/0.01-0.5 mT). The present study concentrates on the significance of the level of electromagnetic field induction in order to determine whether low induction values can restore T lymphocytes adherence capabilities. Testing a subset of 20 patients showed a statistically significant difference (p<0.05) in the in vitro adherence capacity of T lymphocytes between both 0.01 and 0.05, and 0.1 mT induction levels. In the control group (patients diagnosed with chronic sensorineural hearing loss) there was even a statistically significant difference between induction values of 0.05 and 0.01 mT. A statistically significant difference (p<0.05) was also achieved with induction levels of 1 and 10 mT compared to 0.5, 0.1, and 0.05 mT, respectively. Therefore, we concluded that lower induction values resulted in a more biologically significant response.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a buněčná adheze $x účinky záření $7 D002448
- 650 _2
- $a elektromagnetická pole $7 D004574
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a nádory hrtanu $x imunologie $7 D007822
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a nádory hltanu $x imunologie $7 D010610
- 650 _2
- $a T-lymfocyty $x cytologie $x účinky záření $7 D013601
- 650 _2
- $a mladý dospělý $7 D055815
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Hahn, Aleš, $d 1947-2020 $7 nlk19990073180
- 700 1_
- $a Mártonová, Jana
- 700 1_
- $a Ambruš, Miloslav $7 gn_A_00005468
- 700 1_
- $a Dohnalová, Alena
- 700 1_
- $a Nedbalová, Martina
- 700 1_
- $a Jandová, Anna
- 773 0_
- $w MED00174226 $t Electromagnetic biology and medicine $x 1536-8386 $g Roč. 31, č. 2 (2012), s. 166-77
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/22268989 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20130108 $b ABA008
- 991 __
- $a 20220203082607 $b ABA008
- 999 __
- $a ok $b bmc $g 963750 $s 799132
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2012 $b 31 $c 2 $d 166-77 $i 1536-8386 $m Electromagnetic biology and medicine $n Electromagn Biol Med $x MED00174226
- LZP __
- $a Pubmed-20130108