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Comparative study of human monocyte and platelet adhesion to hydrogels in vitro - effect of polymer structure
Jirousková M, Bartunková J, Smetana K Jr, Lukás J, Vacík J, Dyr JE
Jazyk angličtina Země Spojené státy americké
Typ dokumentu srovnávací studie
Grantová podpora
IZ1911
MZ0
CEP - Centrální evidence projektů
Digitální knihovna NLK
Plný text - Část
Zdroj
NLK
ProQuest Central
od 1997-01-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 1997-01-01 do Před 1 rokem
PubMed
15348837
DOI
10.1023/a:1018534111419
Knihovny.cz E-zdroje
- MeSH
- adhezivita trombocytů * MeSH
- hydrogely * MeSH
- lidé MeSH
- monocyty * MeSH
- polymery * MeSH
- techniky in vitro MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- srovnávací studie MeSH
Blood platelet and monocyte adhesion was studied in vitro with respect to the influence of hydrophilic polymer chemical functional groups and their charge. The results showed that the strongest adhesion of human monocytes was to coverslips covered with cationic polymer. Platelet adhesion to all tested polymers proved to be negligible; no differences related to the charge of the polymers used were observed. These results show the obvious difference between the biocompatibility and haemocompatibility in vitro which must be taken into consideration during polymer biological properties testing before clinical trials.
Citace poskytuje Crossref.org
Literatura
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- $a Blood platelet and monocyte adhesion was studied in vitro with respect to the influence of hydrophilic polymer chemical functional groups and their charge. The results showed that the strongest adhesion of human monocytes was to coverslips covered with cationic polymer. Platelet adhesion to all tested polymers proved to be negligible; no differences related to the charge of the polymers used were observed. These results show the obvious difference between the biocompatibility and haemocompatibility in vitro which must be taken into consideration during polymer biological properties testing before clinical trials.
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