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Visfatin and its role in obesity development
J. Stastny, J. Bienertova-Vasku, A. Vasku,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, přehledy
- MeSH
- beta-buňky metabolismus MeSH
- cytokiny metabolismus MeSH
- inzulinová rezistence * MeSH
- lidé MeSH
- lipidy krev MeSH
- nikotinamidfosforibosyltransferasa metabolismus farmakologie MeSH
- obezita metabolismus MeSH
- tuková tkáň metabolismus MeSH
- zánět metabolismus MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Visfatin, a product of PBEF gene, is an adipocytokine that harbours strong insulin-mimetic activity and it has been reported previously to associate with obesity. Recent reports also provide evidence that Visfatin has also important intracellular effects as it is homologous with nicotinamide phosphoribosyltransferase (NAMPT). In this review, we summarize the main documented effects of Visfatin on metabolism in humans, with special emphasis put on the pathways associated with obesity.
Citace poskytuje Crossref.org
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- $a Visfatin, a product of PBEF gene, is an adipocytokine that harbours strong insulin-mimetic activity and it has been reported previously to associate with obesity. Recent reports also provide evidence that Visfatin has also important intracellular effects as it is homologous with nicotinamide phosphoribosyltransferase (NAMPT). In this review, we summarize the main documented effects of Visfatin on metabolism in humans, with special emphasis put on the pathways associated with obesity.
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