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Apoferritin modified magnetic particles as Doxorubicin carriers for anticancer drug delivery

I. Blazkova, HV. Nguyen, S. Dostalova, P. Kopel, M. Stanisavljevic, M. Vaculovicova, M. Stiborova, T. Eckschlager, R. Kizek, V. Adam,

. 2013 ; 14 (7) : 13391-402.

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc13024503

Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution.

Citace poskytuje Crossref.org

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