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Structural alterations of p(HEMA)-collagen implants
M Stol, I Cifkova, V Tyrackova, M Adam
Jazyk angličtina Země Velká Británie
Grantová podpora
IZ221
MZ0
CEP - Centrální evidence projektů
- MeSH
- bérec MeSH
- biodegradace MeSH
- biokompatibilní materiály * MeSH
- inbrední kmeny potkanů MeSH
- kolagen * ultrastruktura MeSH
- krysa rodu rattus MeSH
- mikroskopie elektronová rastrovací MeSH
- polyhydroxyethylmethakrylát * chemie MeSH
- protézy a implantáty * MeSH
- složené pryskyřice MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
Samples of linear (additionally crosslinked) p(HEMA) with different amounts of fibrillar collagen were implanted into the popliteal region of rats. After 3 month, the implanted materials were harvested and examined by SEM. The implants underwent marked structural or morphological changes. While the fibrillar collagen was readily resorbed by invading cells, the synthetic constituent persisted to biodegradation. The p(HEMA) residues were shaped into spherical particles, approx. 1-15 microns in diameter. The possible fate of these microparticles in the host organism is discussed.
Citace poskytuje Crossref.org
Literatura
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