-
Je něco špatně v tomto záznamu ?
Kardiolipín, esenciálny fosfolipid biogenézy a funkcie mitochondrií
[Cardiolipin, essential phospholipid in biogenesis and function of mitochondria]
V. Palovičová, M. Obernauerová
Jazyk slovenština Země Česko
- MeSH
- apoptóza MeSH
- Barthův syndrom etiologie MeSH
- biogeneze organel * MeSH
- buněčná membrána fyziologie MeSH
- Ca2+-ATPasy MeSH
- fosfolipidy biosyntéza fyziologie MeSH
- homeostáza MeSH
- kardiolipiny * biosyntéza fyziologie metabolismus MeSH
- kardiovaskulární nemoci etiologie MeSH
- lidé MeSH
- mitochondriální ADP/ATP-translokasy MeSH
- mitochondriální protonové ATPasy MeSH
- mitochondrie * fyziologie chemie MeSH
- nemoci endokrinního systému etiologie MeSH
- neurodegenerativní nemoci etiologie MeSH
- oxidační stres MeSH
- peroxidace lipidů MeSH
- reaktivní formy kyslíku MeSH
- Check Tag
- lidé MeSH
Cardiolipin, an anionic phospholipid, in the inner mitochondrial membrane is involved in the regulation of mitochondrial bioenergetics and in oxidative phosphorylation. In addition, cardiolipin plays also some role in mitochondria-dependent steps of apoptosis and in mitochondrial membrane dynamics. Alterations in cardiolipin structure (remodelling), its content or the composition of acyl chains as the consequences of oxidative damage due to reactive oxygen species (ROS) are proposed to be responsible for the changes in the mitochondrial membrane fluidity, ion permeability and structure/function of the mitochondrial electron-transport chain components. The mitochondrial dysfunction caused by the above events has been associ¬ated with several physiopathological conditions in human tissues, including Barth syndrome, ischemia/reperfusion, different thyroid states, diabetes, aging or heart failure.
Cardiolipin, essential phospholipid in biogenesis and function of mitochondria
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc14048010
- 003
- CZ-PrNML
- 005
- 20140331120929.0
- 007
- ta
- 008
- 140304s2013 xr d f 000 0slo||
- 009
- AR
- 040 __
- $a ABA008 $d ABA008 $e AACR2 $b cze
- 041 0_
- $a slo $b eng
- 044 __
- $a xr
- 100 1_
- $a Palovičová, Viktória $7 _AN077069 $u Department of Microbiology and Virology, Comenius University, Bratislava
- 245 10
- $a Kardiolipín, esenciálny fosfolipid biogenézy a funkcie mitochondrií / $c V. Palovičová, M. Obernauerová
- 246 31
- $a Cardiolipin, essential phospholipid in biogenesis and function of mitochondria
- 504 __
- $a Literatura
- 520 9_
- $a Cardiolipin, an anionic phospholipid, in the inner mitochondrial membrane is involved in the regulation of mitochondrial bioenergetics and in oxidative phosphorylation. In addition, cardiolipin plays also some role in mitochondria-dependent steps of apoptosis and in mitochondrial membrane dynamics. Alterations in cardiolipin structure (remodelling), its content or the composition of acyl chains as the consequences of oxidative damage due to reactive oxygen species (ROS) are proposed to be responsible for the changes in the mitochondrial membrane fluidity, ion permeability and structure/function of the mitochondrial electron-transport chain components. The mitochondrial dysfunction caused by the above events has been associ¬ated with several physiopathological conditions in human tissues, including Barth syndrome, ischemia/reperfusion, different thyroid states, diabetes, aging or heart failure.
- 650 _2
- $a buněčná membrána $x fyziologie $7 D002462
- 650 12
- $a kardiolipiny $x biosyntéza $x fyziologie $x metabolismus $7 D002308
- 650 _2
- $a fosfolipidy $x biosyntéza $x fyziologie $7 D010743
- 650 12
- $a biogeneze organel $7 D001678
- 650 12
- $a mitochondrie $x fyziologie $x chemie $7 D008928
- 650 _2
- $a reaktivní formy kyslíku $7 D017382
- 650 _2
- $a oxidační stres $7 D018384
- 650 _2
- $a mitochondriální protonové ATPasy $7 D025261
- 650 _2
- $a mitochondriální ADP/ATP-translokasy $7 D000226
- 650 _2
- $a peroxidace lipidů $7 D015227
- 650 _2
- $a homeostáza $7 D006706
- 650 _2
- $a Ca2+-ATPasy $7 D000252
- 650 _2
- $a apoptóza $7 D017209
- 650 _2
- $a kardiovaskulární nemoci $x etiologie $7 D002318
- 650 _2
- $a neurodegenerativní nemoci $x etiologie $7 D019636
- 650 _2
- $a Barthův syndrom $x etiologie $7 D056889
- 650 _2
- $a nemoci endokrinního systému $x etiologie $7 D004700
- 650 _2
- $a lidé $7 D006801
- 700 1_
- $a Obernauerová, Margita $7 xx0069964 $u Department of Microbiology and Virology, Comenius University, Bratislava
- 773 0_
- $t Chemické listy $x 0009-2770 $g Roč. 107, č. 12 (2013), s. 936-941 $w MED00011010
- 856 41
- $u http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/586/586 $y domovská stránka časopisu - plný text volně přístupný
- 910 __
- $a ABA008 $b B 1918 $c 395 $z 0 $y 4
- 990 __
- $a 20140304133814 $b ABA008
- 991 __
- $a 20140331121007 $b ABA008
- 999 __
- $a ok $b bmc $g 1015053 $s 846563
- BAS __
- $a 3
- BMC __
- $a 2013 $b 107 $c 12 $d 936-941 $i 0009-2770 $m Chemické listy $n Chem. Listy $x MED00011010
- LZP __
- $c NLK137 $d 20140331 $a NLK 2014-13/dk