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Štúdium molten globulárneho stavu cytochrómu C pomocou viskozimetrie
[Study of the molten globule state of cytochrome C by Viscometry]

M. Stupák, M. Antalík

. 2013 ; 107 (12) : 969-972.

Language Slovak Country Czech Republic

Combination of viscometry and CD spectrometry made it possible to suggest the existence of a new conformational state of cytochrome c at high temperatures and ionic strengths. The molten globule state of cytochrome c was found at acidic pH in the presence of high concentrations of a salt at 20 °C. A low-cooperative conformational change of the cytochrome c to the unfolded state was observed with increasing temperature. Viscometry is a suitable tool for studies of similar processes in biomacromolecules.

Study of the molten globule state of cytochrome C by Viscometry

Bibliography, etc.

Literatura

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$a Combination of viscometry and CD spectrometry made it possible to suggest the existence of a new conformational state of cytochrome c at high temperatures and ionic strengths. The molten globule state of cytochrome c was found at acidic pH in the presence of high concentrations of a salt at 20 °C. A low-cooperative conformational change of the cytochrome c to the unfolded state was observed with increasing temperature. Viscometry is a suitable tool for studies of similar processes in biomacromolecules.
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