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Assessment of activity of matrix metalloproteases 2 and 9 in their interconnection with the level of magnesium ions in the blood of patients with congenital prolapsed of mitral valve
Gulandom Shodikulova
Jazyk angličtina Země Česko
- MeSH
- dospělí MeSH
- ELISA * MeSH
- lidé MeSH
- matrixová metaloproteinasa 2 * krev metabolismus MeSH
- matrixová metaloproteinasa 9 * krev metabolismus MeSH
- mladiství MeSH
- mladý dospělý MeSH
- prolaps mitrální chlopně * krev vrozené MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
The paper carries out comparative analysis of metalloproteases (MMP) 2 and 9, TIMP expression indexes and their interconnection with Mg2 ions, glycosaminоglycans (GAG) and glucuronidase activity in the blood of patients with congenital PMV. 86 persons, of them 36 (41.9%) males and 50 (58.1%) females aged 15-25 (19.9±1.42) years, with etiological signs of primary (idiopathic, congenital) prolapsed of mitral valve (PMV), have been studied. The patients with PMV and regurgitation of I-II degree showed decreased level of Mg2 ions that was simultaneously associated with disturbance of collagen forming processes, increased synthesis of atypical low-molecular GAG, that passed into the blood stream.
Literatura
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- $a Shodikulova, Gulandom $u Samarkand State Medical Institute, Uzbekistan
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- $a The paper carries out comparative analysis of metalloproteases (MMP) 2 and 9, TIMP expression indexes and their interconnection with Mg2 ions, glycosaminоglycans (GAG) and glucuronidase activity in the blood of patients with congenital PMV. 86 persons, of them 36 (41.9%) males and 50 (58.1%) females aged 15-25 (19.9±1.42) years, with etiological signs of primary (idiopathic, congenital) prolapsed of mitral valve (PMV), have been studied. The patients with PMV and regurgitation of I-II degree showed decreased level of Mg2 ions that was simultaneously associated with disturbance of collagen forming processes, increased synthesis of atypical low-molecular GAG, that passed into the blood stream.
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