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Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis
Rachel Urwin, Andrew J. Fox, Martin Musílek, Paula Kriz, Martin C. J. Maiden
Language English Country United States
Document type Research Support, Non-U.S. Gov't
Grant support
IZ3982
MZ0
CEP Register
Digital library NLK
Full text - Article
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from 1975 to 6 months ago
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PubMed
9817895
Knihovny.cz E-resources
- MeSH
- Molecular Sequence Data MeSH
- Neisseria meningitidis genetics chemistry immunology MeSH
- Porins * MeSH
- Bacterial Outer Membrane Proteins genetics chemistry immunology MeSH
- Amino Acid Sequence MeSH
- Serotyping MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.
National Reference Laboratory for Meningococcal Infections NIPH Prague Czech Republic
Public Health Laboratory Withington Hospital Manchester United Kingdom
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- $a The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.
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