-
Je něco špatně v tomto záznamu ?
Pancreatic stone protein - a possible biomarker of multiorgan failure and mortality in children sepsis
Ž. Jiří, M. Kýr, M. Vavřina, M. Fedora,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, pozorovací studie
- MeSH
- biologické markery krev MeSH
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- lithostatin krev MeSH
- mladiství MeSH
- mladý dospělý MeSH
- multiorgánové selhání krev mortalita patologie MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- prognóza MeSH
- prospektivní studie MeSH
- sepse krev mortalita patologie MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. The prognostic value of PSP/reg among critically ill pediatric patients is unknown. The aim of this pilot study was to evaluate PSP/reg in children with systemic inflammatory response syndrome or sepsis. Prospective observational study, a five day evaluation period in children 0-19years old with systemic inflammatory response syndrome or septic state. Blood tests to determine levels of PSP/reg were obtained as long as the patient met the criteria for systemic inflammatory response syndrome or sepsis. PSP/reg levels did not differ between patients with systemic inflammatory response syndrome and septic condition until organ dysfunction signs were present. PSP/reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with MODS. Patients who died tended to have higher PSP/reg levels.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc15008232
- 003
- CZ-PrNML
- 005
- 20180110151207.0
- 007
- ta
- 008
- 150306s2014 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.cyto.2014.01.009 $2 doi
- 035 __
- $a (PubMed)24594294
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Jiří, Žurek $u University Children's Hospital, Department of Anesthesia and Intensive Care, Černopolní 9, Brno 62500, Czech Republic; Masaryk University, Černopolní 9, Brno 62500, Czech Republic. Electronic address: jzurek@fnbrno.cz.
- 245 10
- $a Pancreatic stone protein - a possible biomarker of multiorgan failure and mortality in children sepsis / $c Ž. Jiří, M. Kýr, M. Vavřina, M. Fedora,
- 520 9_
- $a Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. The prognostic value of PSP/reg among critically ill pediatric patients is unknown. The aim of this pilot study was to evaluate PSP/reg in children with systemic inflammatory response syndrome or sepsis. Prospective observational study, a five day evaluation period in children 0-19years old with systemic inflammatory response syndrome or septic state. Blood tests to determine levels of PSP/reg were obtained as long as the patient met the criteria for systemic inflammatory response syndrome or sepsis. PSP/reg levels did not differ between patients with systemic inflammatory response syndrome and septic condition until organ dysfunction signs were present. PSP/reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with MODS. Patients who died tended to have higher PSP/reg levels.
- 650 _2
- $a mladiství $7 D000293
- 650 _2
- $a biologické markery $x krev $7 D015415
- 650 _2
- $a dítě $7 D002648
- 650 _2
- $a předškolní dítě $7 D002675
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a kojenec $7 D007223
- 650 _2
- $a novorozenec $7 D007231
- 650 _2
- $a lithostatin $x krev $7 D051847
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a multiorgánové selhání $x krev $x mortalita $x patologie $7 D009102
- 650 _2
- $a prognóza $7 D011379
- 650 _2
- $a prospektivní studie $7 D011446
- 650 _2
- $a sepse $x krev $x mortalita $x patologie $7 D018805
- 650 _2
- $a mladý dospělý $7 D055815
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a pozorovací studie $7 D064888
- 700 1_
- $a Kýr, Michal $u Masaryk University, Černopolní 9, Brno 62500, Czech Republic. Electronic address: mkyr@fnbrno.cz.
- 700 1_
- $a Vavřina, Martin $u University Children's Hospital, Department of Anesthesia and Intensive Care, Černopolní 9, Brno 62500, Czech Republic; Masaryk University, Černopolní 9, Brno 62500, Czech Republic. Electronic address: martin.vavrina@fnbrno.cz. $7 xx0220124
- 700 1_
- $a Fedora, Michal $u University Children's Hospital, Department of Anesthesia and Intensive Care, Černopolní 9, Brno 62500, Czech Republic; Masaryk University, Černopolní 9, Brno 62500, Czech Republic. Electronic address: mfedora@fnbrno.cz.
- 773 0_
- $w MED00001313 $t Cytokine $x 1096-0023 $g Roč. 66, č. 2 (2014), s. 106-11
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/24594294 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20150306 $b ABA008
- 991 __
- $a 20180110151432 $b ABA008
- 999 __
- $a ok $b bmc $g 1065505 $s 891032
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2014 $b 66 $c 2 $d 106-11 $i 1096-0023 $m Cytokine (Philadelphia, Pa. Print) $n Cytokine $x MED00001313
- LZP __
- $a Pubmed-20150306
