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3D microscopic imaging and evaluation of tubular tissue architecture

J. Janáček, M. Čapek, J. Michálek, P. Karen, L. Kubínová

. 2014 ; 63 (Suppl. 1) : S49-S55.

Language English Country Czech Republic

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

3D microscopy and image analysis provide reliable measurements of length, branching, density, tortuosity and orientation of tubular structures in biological samples. We present a survey of methods for analysis of large samples by measurement of local differences in geometrical characteristics. The methods are demonstrated on the structure of the capillary bed in a rat brain.

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