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Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries
A. Castaño, F. Cutanda, M. Esteban, P. Pärt, C. Navarro, S. Gómez, M. Rosado, A. López, E. López, K. Exley, BK. Schindler, E. Govarts, L. Casteleyn, M. Kolossa-Gehring, U. Fiddicke, H. Koch, J. Angerer, E. Den Hond, G. Schoeters, O. Sepai, M....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
Odkazy
PubMed
25667172
DOI
10.1016/j.envres.2014.10.029
Knihovny.cz E-zdroje
- MeSH
- chemické látky znečišťující vodu analýza MeSH
- dítě MeSH
- dospělí MeSH
- interpretace statistických dat MeSH
- kontaminace potravin analýza MeSH
- lidé středního věku MeSH
- lidé MeSH
- matky MeSH
- městské obyvatelstvo MeSH
- methylortuťné sloučeniny analýza MeSH
- monitorování životního prostředí metody MeSH
- pilotní projekty MeSH
- potrava z moře (živočišná) * MeSH
- preference v jídle * MeSH
- průzkumy a dotazníky MeSH
- studie proveditelnosti MeSH
- venkovské obyvatelstvo MeSH
- vlasy, chlupy chemie MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Evropa MeSH
The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-child pairs from 17 European countries using a strictly harmonized protocol for mercury analysis. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster analysis of consumption habits of the mother-child pairs, the DEMOCOPHES cohort can be classified into two branches of approximately similar size: one with high fish consumption (H) and another with low consumption (L). All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concentration between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish, contribute significantly to the mercury levels in hair. We conclude that additional studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster analysis also showed that 95% of mothers who consume once per week fish only, and no other marine products, have mercury levels 0.55 μg/g. Thus, the 95th percentile of the distribution in this group is only around half the US-EPA recommended threshold of 1 μg/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an additional dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements.
CHU of Liege Laboratory of Clinical Forensic and Environmental Toxicology Liege Belgium
Departament of Public Health University of Copenhagen Copenhagen Demark
Department of Community of Health Health Service Executive Kildare Ireland
Department of Environmental Sciences Jožef Stefan Institute Ljubljana Slovenia
Department of Hygiene Social and Environmental Medicine Ruhr University Bochum Germany
DG Environment Federal Public Service Health Food Chain Safety and Environment Brussels Belgium
Environmental Health Center Cluj Napoca Romania
Environmental Risk and Health Flemish Institute for Technological Research Mol Belgium
Environmental Toxicology Centro Nacional de Sanidad Ambiental 28220 Majadahonda Madrid Spain
Federal Environment Agency Dessau Rosslau Berlin Germany
Federal Office of Public Health Berne Switzerland
Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden
Instituto de Investigacion de Enfermedades Raras Madrid Spain
Laboratoire National de Santé Dudelange Luxembourg
Larnaca General Hospital Larnaca Cyprus
Lisbon Faculty of Medicine Lisbon Portugal
Luxembourg Institute of Science and Technology Louxembourg
National Institute of Environmental Health Budapest Hungary
National Institute of Public Health Prague Czech Republic
Nofer Institute of Occupational Medicine Lodz Poland
Public Analyst's Laboratory Health Service Executive Cork Ireland
Public Health Authority of the Slovak Republic Bratislava Slovak Republic
Public Health England Centre for Radiation Chemical and Environmental Hazards Chilton United Kingdom
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