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Polymer brushes interfacing blood as a route toward high performance blood contacting devices
F. Surman, T. Riedel, M. Bruns, NY. Kostina, Z. Sedláková, C. Rodriguez-Emmenegger,
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
25644402
DOI
10.1002/mabi.201400470
Knihovny.cz E-zdroje
- MeSH
- biokompatibilní potahované materiály chemie MeSH
- bioznečištění MeSH
- buněčná adheze MeSH
- fotoelektronová spektroskopie MeSH
- krev metabolismus MeSH
- lidé MeSH
- mikroskopie atomárních sil MeSH
- plazma bohatá na destičky MeSH
- polymerizace MeSH
- polymery chemická syntéza chemie MeSH
- povrchové vlastnosti MeSH
- spektroskopie infračervená s Fourierovou transformací MeSH
- testování materiálů přístrojové vybavení MeSH
- voda MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
In the current study, well-defined polymer brushes are shown as an effective surface modification to resist the adhesion of whole blood and its components. Poly[oligo(ethylene glycol)methylether methacrylate] (poly(MeOEGMA)), poly(hydroxyethyl methacrylate) (poly(HEMA)), poly[N-(2-hydroxypropyl) methacrylamide] (poly(HPMA)), and poly(carboxybetaine acrylamide) (poly(CBAA)) brushes were grown by surface initiated atom transfer radical polymerization (SI-ATRP) and subsequently characterized by Fourier-transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), dynamic contact angle measurements, atomic force microscopy (AFM), and surface plasmon resonance (SPR) spectroscopy. All brushes decreased the fouling from blood plasma over 95% and prevented the adhesion of platelets, erythrocytes, and leukocytes as evidenced by SPR and SEM measurements.
Institute for Applied Materials Hermann von Helmholtz Platz 1 76344 Eggenstein Leopoldshafen Germany
Citace poskytuje Crossref.org
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