Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Orlistat and phentermine in weight loss in selected Czech population

Vladimir Pavlik, Jana Fajfrova, Jan M. Horacek, Vaclav Safka, Pavla Krutisova, Miroslav Urban, Peter Urban, Jana Gazdackova, Petr Navratil

. 2016 ; 85 (1) : 13-18.

Jazyk angličtina Země Česko

Perzistentní odkaz   https://www.medvik.cz/link/bmc16014766

Aim: To describe effectiveness of orlistat and phentermine in soldiers of the Armed Forces of the Czech Republic. Methods: In ambulatory patients, some anthropometric and biochemical parameters were compared before administration with 120 mg of orlistat three times a day or 15 mg of phentermine once a day. The same parameters were compared after a three-month therapy. This group included 289 patients (238 males and 51 females) who were administered the same dose of orlistat or phentermine for the entire period of time. Results: Statistically significant weight loss in both genders, on average by 4.6 ± 4.2 kg in males and by 5.3 ± 4.3 kg in females, was observed in patients taking orlistat within three months. Statistically significant weight loss, on average by 6.5 ± 6.0 kg in males and by 5.2 ± 4.3 kg in females, was also observed in patients taking phentermine for the same period of time. As for monitored biochemical parameters, a decrease of total cholesterol, HDL cholesterol and glucose at a statistically significant level (p<0.05) was observed in the group of females, the same statistically significant decrease, but in triglycerides, was proved in the group of males. Then a decrease of total cholesterol and increase of HDL cholesterol at a statistically significant level (p<0.001) was observed in the group of males. Conclusion: We can state that in our patients we have proven a positive effect of orlistat or phentermine substitution on their weight reduction.

Citace poskytuje Crossref.org

Bibliografie atd.

Literatura

000      
00000naa a2200000 a 4500
001      
bmc16014766
003      
CZ-PrNML
005      
20200211140053.0
007      
ta
008      
160518s2016 xr f 000 0|eng||
009      
AR
024    7_
$a 10.31482/mmsl.2016.003 $2 doi
040    __
$a ABA008 $d ABA008 $e AACR2 $b cze
041    0_
$a eng
044    __
$a xr
100    1_
$a Pavlík, Vladimír, $d 1969- $7 stk2007405924 $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
245    10
$a Orlistat and phentermine in weight loss in selected Czech population / $c Vladimir Pavlik, Jana Fajfrova, Jan M. Horacek, Vaclav Safka, Pavla Krutisova, Miroslav Urban, Peter Urban, Jana Gazdackova, Petr Navratil
504    __
$a Literatura
520    9_
$a Aim: To describe effectiveness of orlistat and phentermine in soldiers of the Armed Forces of the Czech Republic. Methods: In ambulatory patients, some anthropometric and biochemical parameters were compared before administration with 120 mg of orlistat three times a day or 15 mg of phentermine once a day. The same parameters were compared after a three-month therapy. This group included 289 patients (238 males and 51 females) who were administered the same dose of orlistat or phentermine for the entire period of time. Results: Statistically significant weight loss in both genders, on average by 4.6 ± 4.2 kg in males and by 5.3 ± 4.3 kg in females, was observed in patients taking orlistat within three months. Statistically significant weight loss, on average by 6.5 ± 6.0 kg in males and by 5.2 ± 4.3 kg in females, was also observed in patients taking phentermine for the same period of time. As for monitored biochemical parameters, a decrease of total cholesterol, HDL cholesterol and glucose at a statistically significant level (p<0.05) was observed in the group of females, the same statistically significant decrease, but in triglycerides, was proved in the group of males. Then a decrease of total cholesterol and increase of HDL cholesterol at a statistically significant level (p<0.001) was observed in the group of males. Conclusion: We can state that in our patients we have proven a positive effect of orlistat or phentermine substitution on their weight reduction.
650    12
$a ozbrojené síly $7 D008889
650    12
$a obezita $x diagnóza $x farmakoterapie $x metabolismus $7 D009765
650    12
$a látky proti obezitě $x terapeutické užití $7 D019440
650    _2
$a laktony $x farmakologie $x terapeutické užití $7 D007783
650    _2
$a fentermin $x farmakologie $x terapeutické užití $7 D010645
650    _2
$a hmotnostní úbytek $x účinky léků $7 D015431
650    _2
$a změny tělesné hmotnosti $7 D001836
650    _2
$a cholesterol $x krev $x metabolismus $7 D002784
650    _2
$a triglyceridy $x krev $x metabolismus $7 D014280
650    _2
$a krevní glukóza $x účinky léků $7 D001786
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé $7 D006801
650    _2
$a ženské pohlaví $7 D005260
700    1_
$a Fajfrová, Jana, $d 1979- $7 xx0107406 $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Horáček, Jan $7 xx0040415 $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Šafka, Václav $7 xx0110558 $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Krutisova, Pavla $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Urban, Miroslav $7 xx0232751 $u Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Urban, Peter $7 xx0136439 $u First Faculty of Medicine, Charles University, Prague
700    1_
$a Gazdackova, Jana $u Language Centre, Faculty of Military Health Sciences, University of Defence, Hradec Králové
700    1_
$a Navrátil, Petr $7 _AN072672 $u Military Medical Department, Division of Support, Minsitry of Defence, Prague
773    0_
$t Vojenské zdravotnické listy $x 0372-7025 $g Roč. 85, č. 1 (2016), s. 13-18 $w MED00011116
856    41
$u http://www.mmsl.cz/archive $y domovská stránka časopisu
910    __
$a ABA008 $b A 3 $c 1073 $y 4 $z 0
990    __
$a 20150120115154 $b ABA008
991    __
$a 20200211140447 $b ABA008
999    __
$a ok $b bmc $g 1124945 $s 939186
BAS    __
$a 3
BMC    __
$a 2016 $b 85 $c 1 $d 13-18 $i 0372-7025 $m Vojenské zdravotnické listy $x MED00011116
LZP    __
$c NLK125 $d 20160624 $a NLK 2016-20/dk

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace