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Technical concept of 3D printed fluidic biosensor with polydimethylsiloxane chip based on fluorescence detection system
Jan Zitka, Zbynek Heger, Ondrej Zitka, Vojtech Adam, Rene Kizek
Language English Country Czech Republic
Document type Research Support, Non-U.S. Gov't
NLK
Open Access Digital Library
from 2014-01-01
ROAD: Directory of Open Access Scholarly Resources
from 2014 to 2015
- MeSH
- Printing, Three-Dimensional * MeSH
- Acrylonitrile MeSH
- Biomarkers MeSH
- Biosensing Techniques * instrumentation utilization MeSH
- Butadienes MeSH
- Dimethylpolysiloxanes MeSH
- Fluorescence MeSH
- Lab-On-A-Chip Devices * MeSH
- Styrenes MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
There is a rapidly growing interest in low-cost, fast and sensitive biosensors. In particular, direct determination of important metabolites, serving as biomarkers of various pathological states can significantly enhance the treatment successes. In our study, we introduce a technical concept of a 3D printed biosensor, which employs polydimethylsiloxane chip with volume of 50 µL as an inert and optically clear reservoir for recognition element and fluorescence detection. By using a 3D printing technology, low production cost and high crafting reproducibility were achieved. Due to a presence of controlled electromagnet, the biosensor can be utilized for a broad spectrum of applications, based on paramagnetic nano- or microscaled materials.
Central European Institute of Technology Brno University of Technology Czech Republic European Union
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- $a Zítka, Jan $7 _AN082271 $u Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnologies, Mendel University in Brno, Czech Republic - European Union; Central European Institute of Technology, Brno University of Technology, Czech Republic - European Union
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- $a Technical concept of 3D printed fluidic biosensor with polydimethylsiloxane chip based on fluorescence detection system / $c Jan Zitka, Zbynek Heger, Ondrej Zitka, Vojtech Adam, Rene Kizek
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- $a There is a rapidly growing interest in low-cost, fast and sensitive biosensors. In particular, direct determination of important metabolites, serving as biomarkers of various pathological states can significantly enhance the treatment successes. In our study, we introduce a technical concept of a 3D printed biosensor, which employs polydimethylsiloxane chip with volume of 50 µL as an inert and optically clear reservoir for recognition element and fluorescence detection. By using a 3D printing technology, low production cost and high crafting reproducibility were achieved. Due to a presence of controlled electromagnet, the biosensor can be utilized for a broad spectrum of applications, based on paramagnetic nano- or microscaled materials.
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- $a Heger, Zbyněk $7 xx0276759 $u Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnologies, Mendel University in Brno, Czech Republic - European Union; Central European Institute of Technology, Brno University of Technology, Czech Republic - European Union
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- $a Zítka, Ondřej $7 xx0116134 $u Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnologies, Mendel University in Brno, Czech Republic - European Union; Central European Institute of Technology, Brno University of Technology, Czech Republic - European Union
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- $a Adam, Vojtěch, $d 1982- $7 xx0064599 $u Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnologies, Mendel University in Brno, Czech Republic - European Union; Central European Institute of Technology, Brno University of Technology, Czech Republic - European Union
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- $a Kizek, René, $d 1972- $7 jn20001005291 $u Department of Chemistry and Biochemistry, Laboratory of Metallomics and Nanotechnologies, Mendel University in Brno, Czech Republic - European Union; Central European Institute of Technology, Brno University of Technology, Czech Republic - European Union
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- $t Journal of Metallomics and Nanotechnologies $x 2336-3940 $g Roč. 2, č. 1 (2015), s. 62-65 $w MED00185603
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